Aydin Naz Bige, Sener Tufan, Kehlibar Ilknur Kiygil, Turkoglu Tansel, Karpuzoglu Osman Eren, Ozkul Vedat, Gercekoglu Hakan
Department of Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Research and Training Hospital, Istanbul, Turkey.
Heart Surg Forum. 2005;8(6):E456-61; discussion E461. doi: 10.1532/HSF98.20051150.
Sternal wound complication is a major concern in bilateral internal thoracic artery grafting. The purpose of this study was to assess whether avoiding cardiopulmonary bypass has beneficial effects with fewer wound complications in patients receiving bilateral internal thoracic artery grafting.
Retrospective review was performed using prospectively gathered data of 69 patients who had undergone elective coronary artery bypass grafting and received conventional pedicled bilateral internal thoracic artery grafting from December 2002 through April 2004 by the same surgical team. The patients were divided into 2 groups: those who underwent coronary artery bypass grafting without cardiopulmonary bypass (off-pump group, n = 41), and those who underwent coronary artery bypass grafting with cardiopulmonary bypass (CPB group, n = 28). Chart review and 3-month follow-up were obtained for all patients. These 2 groups were compared for sternal wound complications and preoperative, intraoperative, and postoperative variables.
Deep sternal wound infection (SWI) was seen in 1 patient (2.4%), superficial SWI in 2 patients (4.8%), and sternal dehiscence in 1 patient (2.4%) in the off-pump group. Deep SWI was seen in no patients, superficial SWI in 2 patients (7.1%) and sternal dehiscence in 2 patients (7.1%) in the CPB group. No statistically significant difference in the frequency of occurrence of sternal complications was detected between the 2 study groups.
The results suggest that the avoidance of CPB has no beneficial effect on the number of sternal wound complications in patients receiving bilateral internal thoracic artery grafting. However, further prospective, randomized studies on large patient groups are required to assess this finding.
在双侧胸廓内动脉移植术中,胸骨伤口并发症是一个主要问题。本研究的目的是评估在接受双侧胸廓内动脉移植的患者中,避免体外循环是否对减少伤口并发症有有益影响。
回顾性分析了2002年12月至2004年4月间由同一手术团队进行择期冠状动脉旁路移植术并接受传统带蒂双侧胸廓内动脉移植术的69例患者的前瞻性收集数据。患者分为两组:一组接受非体外循环冠状动脉旁路移植术(非体外循环组,n = 41),另一组接受体外循环冠状动脉旁路移植术(CPB组,n = 28)。对所有患者进行病历审查和3个月随访。比较两组患者的胸骨伤口并发症以及术前、术中和术后变量。
非体外循环组有1例患者发生深部胸骨伤口感染(SWI)(2.4%),2例患者发生浅表SWI(4.8%),1例患者发生胸骨裂开(2.4%)。CPB组无患者发生深部SWI,2例患者发生浅表SWI(7.1%),2例患者发生胸骨裂开(7.1%)。两个研究组之间胸骨并发症的发生率没有统计学上的显著差异。
结果表明,在接受双侧胸廓内动脉移植的患者中,避免CPB对胸骨伤口并发症的数量没有有益影响。然而,需要对大量患者群体进行进一步的前瞻性随机研究来评估这一发现。