Uhlig T, Haavardsholm E A, Kvien T K
National Resource Center for Rehabilitation in Rheumatology, Department of Rheumatology, Diakonhjemmet Hospital, Box 23 Vinderen, N-0319 Oslo, Norway.
Rheumatology (Oxford). 2006 Apr;45(4):454-8. doi: 10.1093/rheumatology/kei181. Epub 2005 Nov 15.
Physical disability in patients with rheumatoid arthritis (RA) is often assessed by questionnaires. We compared the Health Assessment Questionnaire (HAQ) with the modified HAQ (MHAQ) in a cohort of RA patients across various levels of disability, and examined correlations with other measures of physical function.
Patients with RA (n = 182) completed self-report questionnaires assessing functional capacity. Instruments included the MHAQ and HAQ completed separately, as well as SF-36 and the Arthritis Impact Measurement Scales (AIMS). Scores from unadjusted and adjusted HAQ were compared with MHAQ at various disability levels.
A clear ceiling effect with aggregation of normal scores for physical function was observed for MHAQ (23%) and HAQ (12%), but not for SF-36 (4%) or AIMS (5%). The correlations between adjusted/unadjusted HAQ and MHAQ scores were 0.85/0.88. A discrepancy in HAQ and MHAQ scores was observed in patients with high levels of disability, especially when MHAQ was compared with the adjusted final HAQ score. Adjustment of HAQ by aids or help increased the final score by an average of 0.15, and both adjusted and unadjusted HAQ scores were numerically clearly higher (mean 0.45 and 0.30, respectively) than the MHAQ score.
The present findings indicate that MHAQ and HAQ may be applicable as measures of physical capacity in RA patients, but clinicians and researchers should select the appropriate instrument for the setting, and be aware of differences in scores, especially at different disability levels.
类风湿关节炎(RA)患者的身体残疾情况通常通过问卷进行评估。我们在不同残疾程度的RA患者队列中比较了健康评估问卷(HAQ)和改良健康评估问卷(MHAQ),并研究了它们与其他身体功能测量指标的相关性。
182例RA患者完成了评估功能能力的自我报告问卷。评估工具包括分别完成的MHAQ和HAQ,以及SF-36和关节炎影响测量量表(AIMS)。在不同残疾水平下,将未调整和调整后的HAQ得分与MHAQ得分进行比较。
观察到MHAQ(23%)和HAQ(12%)在身体功能正常得分汇总时有明显的天花板效应,但SF-36(4%)或AIMS(5%)没有。调整后/未调整的HAQ与MHAQ得分之间的相关性为0.85/0.88。在残疾程度较高的患者中,HAQ和MHAQ得分存在差异,尤其是将MHAQ与调整后的最终HAQ得分进行比较时。使用辅助工具或他人帮助对HAQ进行调整后,最终得分平均提高了0.15,调整后和未调整的HAQ得分在数值上均明显高于MHAQ得分(分别为平均0.45和0.30)。
目前的研究结果表明,MHAQ和HAQ可作为RA患者身体能力的测量指标,但临床医生和研究人员应根据具体情况选择合适的工具,并注意得分差异,尤其是在不同残疾水平时。