Law W L, Lam C M, Lee Y M
Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Pokfulam Road, Hong Kong.
Br J Surg. 2006 Jan;93(1):94-9. doi: 10.1002/bjs.5183.
This study evaluated the Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM), Portsmouth (P) POSSUM and colorectal (CR) POSSUM in laparoscopic colorectal resection.
Observed mortality and morbidity rates in 400 patients who underwent laparoscopic colorectal resection were compared with those predicted by POSSUM, P-POSSUM and CR-POSSUM.
Observed mortality and morbidity rates were 0.5 and 19.0 per cent respectively. Mortality rates predicted by POSSUM, P-POSSUM and CR-POSSUM were 10.8, 4.0 and 5.6 per cent respectively, and the morbidity rate predicted by POSSUM was 43.0 per cent. The predicted and observed mortality and morbidity rates showed significant lack of fit. The conversion rate to open surgery was 11.5 per cent. The mortality rate for patients having conversion was 2 per cent and was not significantly different to that predicted by P-POSSUM (4 per cent; P = 0.493) or CR-POSSUM (5 per cent; P = 0.370). In this group, the observed and POSSUM-predicted morbidity rates were also similar (43 versus 48 per cent respectively; P = 0.104).
POSSUM, P-POSSUM and CR-POSSUM overestimated mortality and morbidity in patients who underwent laparoscopic colorectal resection. However, the mortality rate in patients who required conversion fitted the models of P-POSSUM and CR-POSSUM, and the morbidity rate was comparable to that predicted by POSSUM.
本研究评估了用于计算死亡率和发病率的生理与手术严重程度评分系统(POSSUM)、朴茨茅斯(P)POSSUM以及结直肠(CR)POSSUM在腹腔镜结直肠切除术中的应用情况。
将400例行腹腔镜结直肠切除术患者的观察到的死亡率和发病率与POSSUM、P-POSSUM和CR-POSSUM预测的结果进行比较。
观察到的死亡率和发病率分别为0.5%和19.0%。POSSUM、P-POSSUM和CR-POSSUM预测的死亡率分别为10.8%、4.0%和5.6%,POSSUM预测的发病率为43.0%。预测的和观察到的死亡率及发病率显示出明显的拟合不足。转为开放手术的比例为11.5%。转为开放手术患者的死亡率为2%,与P-POSSUM预测的死亡率(4%;P = 0.493)或CR-POSSUM预测的死亡率(5%;P = 0.370)相比无显著差异。在该组中,观察到的发病率与POSSUM预测的发病率也相似(分别为43%和48%;P = 0.104)。
POSSUM、P-POSSUM和CR-POSSUM高估了接受腹腔镜结直肠切除术患者的死亡率和发病率。然而,需要转为开放手术患者的死亡率符合P-POSSUM和CR-POSSUM模型,发病率与POSSUM预测的发病率相当。