Jutiviboonsuk Aranya, Zhang Hongjie, Tan Ghee Teng, Ma Cuiying, Van Hung Nguyen, Manh Cuong Nguyen, Bunyapraphatsara Nuntavan, Soejarto D Doel, Fong Harry H S
Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, 447 Si Ayutthaya Road, Ratchathewi District, Bangkok 10400, Thailand.
Phytochemistry. 2005 Dec;66(23):2745-51. doi: 10.1016/j.phytochem.2005.09.025. Epub 2005 Nov 9.
Bioassay directed-fractionation led to isolation of 12 compounds from the roots of Bursera tonkinensis Guillaum (Burseraceae), including burselignan, bursephenylpropane, and burseneolignan. Of the 12 compounds, only 4'-demethyldesoxypodophyllotoxin exhibited significant cytotoxic activities against KB, Col2 and LNCaP cell lines.
生物活性导向分离法从东京裂榄（橄榄科）的根中分离出12种化合物，包括裂榄木脂素、裂榄苯丙烷和裂榄新木脂素。在这12种化合物中，只有4'-去甲基脱氧鬼臼毒素对KB、Col2和LNCaP细胞系表现出显著的细胞毒性活性。
