Lynn L A, Kissinger J F
Asheboro Internal Medicine Associates, N.C.
Heart Lung. 1992 Jul-Aug;21(4):365-71.
The effect of caffeine on heart rate, blood pressure, and cardiac rhythm has long been a controversial issue. A review of the literature reveals numerous articles evaluating the effects of caffeine on normal subjects, fewer evaluating the effects of caffeine on patients with cardiac disease and patients after myocardial infarction. Although the findings for the various populations have been inconsistent, recent studies with large cohorts have clarified the issue. Moderate consumption of caffeine does not significantly increase the risk of a coronary event nor increase the frequency of cardiac arrhythmias. This conclusion applies to healthy persons, patients with ischemic heart disease, and those with serious ventricular ectopy. Patients with cardiac disease should be allowed to consume four to five cups of caffeinated beverages per day while in the coronary care unit or progressive care unit under the surveillance of nursing staff.
咖啡因对心率、血压和心律的影响长期以来一直是个有争议的问题。文献综述显示，有大量文章评估咖啡因对正常受试者的影响，而评估咖啡因对心脏病患者和心肌梗死后患者影响的文章较少。尽管针对不同人群的研究结果并不一致，但最近对大量队列的研究已经澄清了这个问题。适度摄入咖啡因不会显著增加冠心病事件的风险，也不会增加心律失常的频率。这一结论适用于健康人、缺血性心脏病患者以及有严重室性早搏的患者。在冠心病监护病房或逐步护理病房，心脏病患者在护理人员的监测下，每天可饮用四至五杯含咖啡因的饮料。
