肺结核患者的[123I]异丁基安非他明肺闪烁显像

Lung scintigraphy with [123I]IMP in patients with pulmonary tuberculosis.

作者信息

Nagamachi S, Inoue K, Hoshi H, Jinnouchi S, Ohonishi T, Futami S, Watanabe K, Wakisaka M, Morotomi Y

机构信息

Department of Radiology, Miyazaki Medical College, Miyazakiken, Japan.

出版信息

Int J Rad Appl Instrum B. 1992 Apr;19(3):399-404. doi: 10.1016/0883-2897(92)90125-i.

DOI:10.1016/0883-2897(92)90125-i

PMID:1629028

Abstract

Lung scintigraphy using N-isopropyl-p-[123I]iodoamphetamine (IMP) was performed on 26 patients with pulmonary tuberculosis. Early (5 min after injection) and late images (4 h after injection) were obtained with a large-field gamma-camera equipped with a digital computer. Lung scintigraphy using [99mTc]MAA (MAA) was also done. Although early IMP images showed the same findings as [99mTc]MAA, images, a discrepancy between delayed IMP images and [99mTc]MAA images was seen in some patients. Increment of activities seen in late images was demonstrated in most patients whose chest x-ray findings included exudative inflammatory changes. Uptake and clearance of IMP was considered to be affected by the active phase of pulmonary tuberculosis.

摘要

对26例肺结核患者进行了使用N-异丙基-p-[123I]碘安非他明（IMP）的肺闪烁扫描。使用配备数字计算机的大视野γ相机获取早期（注射后5分钟）和晚期图像（注射后4小时）。还进行了使用[99mTc]MAA（MAA）的肺闪烁扫描。尽管早期IMP图像显示出与[99mTc]MAA图像相同的结果，但在一些患者中，延迟IMP图像与[99mTc]MAA图像之间存在差异。在大多数胸部X线检查结果包括渗出性炎症改变的患者中，晚期图像中可见活性增加。IMP的摄取和清除被认为受肺结核活动期的影响。