两亲性聚酰胺-胺（PAMAM）树枝状大分子在朗缪尔和朗缪尔-布洛杰特膜中的结构研究。

A structural study of amphiphilic PAMAM (poly(amido amine)) dendrimers in Langmuir and Langmuir-Blodgett films.

作者信息

Sui Guodong, Mabrouki Mustapha, Ma Yuqiu, Micic Miodrag, Leblanc Roger M

机构信息

Center for Supramolecular Science and Center for Advanced Microscopy, Department of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, Florida 33124, USA.

出版信息

J Colloid Interface Sci. 2002 Jun 15;250(2):364-70. doi: 10.1006/jcis.2002.8351.

DOI:10.1006/jcis.2002.8351

PMID:16290673

Abstract

Two amphiphilic PAMAM dendrimers are synthesized by attaching 12-hydroxydodecanoic acid (HA) chains to a poly(amido amine) (PAMAM) dendrimer core (including generation I and generation II). The limiting molecular area obtained from the surface pressure-area isotherm at the air/water interface suggests the edge-on configuration for both dendrimers in Langmuir films. The edge-on arrangement is also supported by the atomic force microscopic (AFM) studies of the Langmuir-Blodgett films.

摘要

通过将12-羟基十二烷酸（HA）链连接到聚（酰胺胺）（PAMAM）树枝状大分子核（包括第一代和第二代）上，合成了两种两亲性PAMAM树枝状大分子。在空气/水界面处由表面压力-面积等温线获得的极限分子面积表明，在Langmuir膜中两种树枝状大分子均呈边缘排列构型。Langmuir-Blodgett膜的原子力显微镜（AFM）研究也支持了这种边缘排列方式。