Eisele J H, Wuyam B, Savourey G, Eterradossi J, Bittel J H, Benchetrit G
Laboratoire de Physiologie, Faculté de Médecine de Grenoble, France.
J Appl Physiol (1985). 1992 Jun;72(6):2446-53. doi: 10.1152/jappl.1992.72.6.2446.
Breathing was recorded via a pulsed ultrasonic flowmeter in 11 healthy subjects, at rest and during steady-state exercise (at 50% of their maximal O2 consumption) at both sea level (200 m) and simulated altitude (4,500 m in a hypobaric chamber). The pattern of breathing was quantified breath by breath in terms of classical respiratory variables (tidal volume and inspiratory and expiratory times), and the shape of the entire airflow profile was quantified by harmonic analysis. Statistical tests were used to compare the within-individual with the between-individual variations. In comparing the sea level vs. altitude rest (16% increase in ventilation) and sea level vs. altitude exercise (40% increase in ventilation) airflow profiles, we found a significantly greater resemblance within the individual than between individuals. Comparisons of sea level rest and exercise (295% increase in ventilation) and altitude rest and exercise (375% increase in ventilation) revealed no similarity within individuals. Despite airflow profile changes between rest and exercise, it is still possible to attest to a diversity of flow profile between individuals during exercise. Hypoxia at rest or during exercise does not alter the phenomenon of the individuality of breathing patterns.
通过脉冲式超声波流量计对11名健康受试者在海平面（200米）和模拟海拔（在低压舱内4500米）条件下静息和稳态运动（耗氧量达到最大耗氧量的50%）时的呼吸情况进行记录。呼吸模式根据经典呼吸变量（潮气量、吸气时间和呼气时间）逐次呼吸进行量化，整个气流轮廓的形状通过谐波分析进行量化。使用统计检验来比较个体内部与个体之间的差异。在比较海平面与海拔静息（通气量增加16%）以及海平面与海拔运动（通气量增加40%）时的气流轮廓时，我们发现个体内部的相似性显著大于个体之间。海平面静息与运动（通气量增加295%）以及海拔静息与运动（通气量增加375%）的比较显示个体内部不存在相似性。尽管静息和运动时气流轮廓发生了变化，但仍有可能证明运动期间个体之间气流轮廓的多样性。静息或运动时的低氧不会改变呼吸模式个体性的现象。
