Moffitt Terrie E
Institute of Psychiatry, King's College London, London SE5 8AF, United Kingdom.
Adv Genet. 2005;55:41-104. doi: 10.1016/S0065-2660(05)55003-X.
This article reviews behavioral-genetic research into human antisocial behavior. The focus is on studies of antisocial behavior that have been leading the way in investigating environmental and genetic influences on human behavior. The first generation of studies, which provided quantitative estimates attesting that genes and environments each influence about half of the population's variation in antisocial behaviors is interpreted. Then how behavioral-genetic methods are being applied to test developmental theory and to detect environmental causes of antisocial behavior is illustrated. Evidence for interactions between genes and the environment in the etiology of antisocial behavior is also examined. The article ends by envisioning future work on gene-environment interplay in the etiology of antisocial behavior.
本文回顾了关于人类反社会行为的行为遗传学研究。重点是那些在研究环境和基因对人类行为的影响方面处于领先地位的反社会行为研究。第一代研究提供了定量估计,证明基因和环境各自影响了大约一半的人群在反社会行为上的差异,本文对这些研究进行了解读。接着说明了行为遗传学方法如何被用于检验发展理论以及检测反社会行为的环境成因。还考察了反社会行为病因中基因与环境相互作用的证据。文章最后展望了未来在反社会行为病因中基因 - 环境相互作用方面的研究工作。