Brandt Ingeborg, Sticker Elisabeth J, Gausche Ruth, Lentze Michael J
Children's Hospital Medical Center, Department of Pediatrics, University of Bonn, Bonn, Germany.
J Pediatr. 2005 Nov;147(5):662-8. doi: 10.1016/j.jpeds.2005.06.034.
To analyze linear growth of very low birth weight (VLBW), small for gestational age (SGA; < 10th percentile) preterm infants from birth as to catch-up or no catch-up growth.
VLBW SGA preterm infants (n = 46) with primarily symmetric intrauterine growth restriction from the Bonn Longitudinal Study were compared with 62 appropriate for gestational age (AGA) VLBW preterm and 73 term infants and with their parents.
Forty-six percent of VLBW SGA (21 of 46) had complete height catch-up by adult age, and most became taller than target height (TH) (15 of 21; 71%). The others did not catch up; most of them remained shorter than TH (18 of 25; 72%) after initial catch-up followed by catch-down growth. Mean adult height z-score was lower than that for birth length. Mean body mass index was similar in the catch-up and no catch-up groups (21.8 and 21.3, respectively) and lower than in the controls (23.2). Approximately 1/2 of the head circumference (HC) catch-up children achieved height catch-up as well.
Height catch-up extended beyond age 6 years, independent of HC growth. We could not predict height catch-down or successful catch-up.
分析极低出生体重（VLBW）、小于胎龄（SGA；<第10百分位数）的早产婴儿从出生起的线性生长情况，以确定其是否实现追赶生长。
将来自波恩纵向研究的46例主要为对称性宫内生长受限的极低出生体重小于胎龄早产婴儿与62例适于胎龄的极低出生体重早产儿、73例足月儿及其父母进行比较。
46%的极低出生体重小于胎龄儿（46例中的21例）到成年时身高完全追赶上来，且大多数超过了目标身高（TH）（21例中的15例；71%）。其他婴儿未实现追赶生长；在最初出现追赶生长随后又出现追赶下降生长后，他们中的大多数仍低于目标身高（25例中的18例；72%）。成年时平均身高z评分低于出生时身长的z评分。追赶生长组和未追赶生长组的平均体重指数相似（分别为21.8和21.3），且低于对照组（23.2）。约一半头围（HC）实现追赶生长的儿童身高也实现了追赶生长。
身高追赶生长持续到6岁以后，与头围生长无关。我们无法预测身高追赶下降或成功的追赶生长情况。
