[原位膀胱替代术治疗间质性膀胱炎]
[Orthotopic bladder substitution in the treatment of interstitial cystitis].
作者信息
Navalón Verdejo Pedro, Ordoño Domínguez Felipe, De la Torre Abril Luis, Sánchez Ballester Francisco, Escudero Joaquín Juan, Ramos de Campos Macarena, Ramada Benlloch Francisco
机构信息
Servicio de Urologia, Consorcio Hospital General Universitario, Valencia, España,
出版信息
Arch Esp Urol. 2005 Sep;58(7):605-10. doi: 10.4321/s0004-06142005000700004.
OBJECTIVES
To point out the efficacy of supra trigonal cystectomy with orthotopic substitution iliocystoplasty in the treatment of advanced interstitial cystitis (IC).
METHODS
We study the results obtained in four women suffering IC nonrespondent to conservative treatment who underwent the procedure. All patients comply with classic diagnostic criteria of IC, presenting long-lasting symptoms, between 4 and 8 years (mean 5.6), and voiding frequency of near one-hour day and night.
RESULTS
Mean postoperative follow-up was 32 months (18 to 56); post operative evaluation included clinical evaluation, ultrasound, urodynamic studies, and radiological tests. Suprapubic pain disappeared in all cases, as well as pre-op lower urinary tract symptoms, with good control of urinary frequency day and night being evident in the immediate postoperative period. All patients referred high satisfaction with the outcome.
CONCLUSIONS
When conservative treatment fails, supratrigonal cystectomy with orthotopic neobladder substitution is a valid therapeutic option in IC patients who comply with classic diagnostic criteria.
目的
指出三角区上方囊肿切除术联合原位替代回肠膀胱扩大术治疗晚期间质性膀胱炎（IC）的疗效。
方法
我们研究了4例接受该手术的对保守治疗无反应的IC女性患者的治疗结果。所有患者均符合IC的经典诊断标准，症状持续时间长，为4至8年（平均5.6年），日夜排尿频率接近每小时1次。
结果
术后平均随访32个月（18至56个月）；术后评估包括临床评估、超声、尿动力学研究和放射学检查。所有病例耻骨上疼痛均消失，术前下尿路症状也消失，术后即刻日夜尿频得到良好控制。所有患者对治疗结果均表示高度满意。
结论
当保守治疗失败时，对于符合经典诊断标准的IC患者，三角区上方囊肿切除术联合原位新膀胱替代术是一种有效的治疗选择。
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