McMahon M Molly, Hurley Daniel L, Kamath Patrick S, Mueller Paul S
Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA.
Mayo Clin Proc. 2005 Nov;80(11):1461-76. doi: 10.4065/80.11.1461.
Clinicians frequently care for patients in whom long-term enteral tube feeding is being considered. The substantial increase in the use of endoscopically placed tubes for long-term feeding reflects the aging population, advances in medicine and technology, and inadequate advance care planning. Physicians should address advance care planning with all patients at the earliest opportunity. Prospective randomized trials measuring clinical outcomes for patients receiving long-term tube feeding are understandably limited. In addition, confusion regarding medical and ethical guidelines for long-term tube feeding often exists among clinicians, patients, and surrogate decision makers. Therefore, we discuss the physiology and clinical tolerance of limited oral nutritional intake, the prevalence of and Indications for long-term tube feeding, the endoscopic procedures and their complications, the reported medical and quality-of-life outcomes, and the critical importance of advance care planning. We present our multidisciplinary approach that combines medical, nutritional, and ethical principles for the care of these patients.
临床医生经常会诊治那些正在考虑长期肠内管饲的患者。内镜下放置的长期喂养管使用量的大幅增加反映了人口老龄化、医学和技术的进步以及预先护理计划的不足。医生应尽早与所有患者讨论预先护理计划。可以理解的是,衡量长期管饲患者临床结局的前瞻性随机试验有限。此外,临床医生、患者和替代决策者之间常常存在关于长期管饲的医学和伦理准则的困惑。因此,我们讨论了有限经口营养摄入的生理学和临床耐受性、长期管饲的患病率和适应证、内镜操作及其并发症、报告的医学和生活质量结局,以及预先护理计划的至关重要性。我们提出了一种多学科方法,将医学、营养和伦理原则结合起来用于这些患者的护理。