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痴呆患者胃造口管置入的并发症:一项全国住院患者分析。

Complications of gastrostomy tube placement in patients with dementia: a national inpatient analysis.

作者信息

Goble Spencer R, Leventhal Thomas M

机构信息

Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, MMC 36, 420 Delaware Street S.E., Minneapolis, MN, 55455, USA.

University of Minnesota, Mayo Memorial Building, MMC 250, 420 Delaware Street S.E, Minneapolis, MN, 55455, USA.

出版信息

Surg Endosc. 2025 Jun 30. doi: 10.1007/s00464-025-11923-x.

Abstract

BACKGROUND

Gastrostomy tubes have not been shown to improve long-term outcomes in patients with dementia, yet the risk of short-term complications have not been well characterized in this population.

METHODS

This is a cross-sectional retrospective assessment of the National Inpatient Sample from 2016 to 2022. We compared outcomes in patients with dementia and those without dementia. Evaluated outcomes including procedural complications, in-hospital mortality, and discharge to home among others. Assessed procedural complications included peritonitis, hemorrhage, infection and colon perforation.

RESULTS

A total of 1,171,230 hospitalizations were identified, 241,380 (20.6%) were for patients with dementia. Patients with dementia were older (mean 76.3 vs 64.1 years, p < 0.001), more likely to be female (49.4% vs 41.7%, p < 0.001) and Black (27.5% vs 19.6%, p < 0.001). Procedural complications were less common in patients with dementia (3.6% vs 4.6%, ARD = 10:1000) although surgical site infection was increased (1.6% vs 1.4%, aOR = 1.58, 95% CI 1.44-1.73, p < 0.001). Mortality was also decreased in patients with dementia (6.4% vs 8.2%, ARD = 19:1000). Patients with dementia were less likely to discharge to home (20.8% vs 33.8%, aOR = 0.64, 95% CI 0.63-0.66, p < 0.001).

CONCLUSIONS

Gastrostomy tube placement complications do not appear to be increased in patients with dementia. However, those who undergo gastrostomy tube placement are less likely to discharge to home which has important quality of life implications.

摘要

背景

胃造口管尚未被证明能改善痴呆患者的长期预后,但该人群短期并发症的风险尚未得到充分描述。

方法

这是一项对2016年至2022年全国住院患者样本的横断面回顾性评估。我们比较了痴呆患者和非痴呆患者的预后。评估的预后包括手术并发症、住院死亡率和出院回家情况等。评估的手术并发症包括腹膜炎、出血、感染和结肠穿孔。

结果

共确定了1,171,230例住院病例,其中241,380例(20.6%)为痴呆患者。痴呆患者年龄更大(平均76.3岁对64.1岁,p<0.001),女性比例更高(49.4%对41.7%,p<0.001),黑人比例更高(27.5%对19.6%,p<0.001)。痴呆患者的手术并发症较少见(3.6%对4.6%,绝对风险差=10/1000),尽管手术部位感染有所增加(1.6%对1.4%,调整后比值比=1.58,95%置信区间1.44-1.73,p<0.001)。痴呆患者的死亡率也较低(6.4%对8.2%,绝对风险差=19/1000)。痴呆患者出院回家的可能性较小(20.8%对33.8%,调整后比值比=0.64,95%置信区间0.63-0.66,p<0.001)。

结论

痴呆患者胃造口管置入并发症似乎并未增加。然而,接受胃造口管置入的患者出院回家的可能性较小,这对生活质量有重要影响。

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