Yaranal P J, Basu D, Narayanan P, Mahadevan S
Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
Indian J Pathol Microbiol. 2004 Apr;47(2):233-5.
A twelve-year-old boy presented with recurrent episodes of anemia. Complete blood counts showed pancytopenia. Bone marrow was hypercellular with erythroid hyperplasia and depleted stores of iron. Positive Ham's test and sucrose lysis test revealed that he had paroxysmal nocturnal hemoglobinuria. There was a delay of nearly two years in the diagnosis in this patient. Paroxysmal nocturnal hemoglobinuria is rare in childhood. It must however be considered in a child who presents with unexplained anemia or bone marrow failure so that an early and accurate diagnosis is reached.
一名12岁男孩出现反复贫血发作。全血细胞计数显示全血细胞减少。骨髓细胞增多，红系增生，铁储备减少。酸溶血试验（Ham试验）和蔗糖溶血试验阳性，表明他患有阵发性夜间血红蛋白尿。该患者诊断延迟了近两年。阵发性夜间血红蛋白尿在儿童期罕见。然而，对于出现不明原因贫血或骨髓衰竭的儿童，必须考虑到这种疾病，以便早期准确诊断。
