Okada Y, Ikeda I, Zhang T, Wang Y
Department of Neurology, University of New Mexico School of Medicine, Albuquerque, New Mexico, 87131-0001, USA.
Clin EEG Neurosci. 2005 Oct;36(4):285-92. doi: 10.1177/155005940503600408.
High-frequency signals (HFSs) between 400-1500 Hz in Magnetoencephalography (MEG) and Electroencephalography (EEG) provide a new window in electrophysiological analysis of the somatosensory system in humans and in other animals. The HFS in the primary somatosensory (SI) cortex precedes the conventional N20. In the swine model, they appear to be due to spiking in thalamocortical axonal terminals and in the soma and dendrites of cortical neurons. These spiking activities seem to activate slower conductances in the pyramidal cells in layers II-III and V, which give rise to N20. The HFS monitoring may be useful for separately evaluating the electrophysiology of the subcortical and cortical components of the somatosensory pathway.
脑磁图（MEG）和脑电图（EEG）中400 - 1500赫兹之间的高频信号（HFSs）为人类和其他动物体感系统的电生理分析提供了一个新窗口。初级体感（SI）皮层中的HFS先于传统的N20出现。在猪模型中，它们似乎是由于丘脑皮质轴突终末以及皮质神经元的胞体和树突中的动作电位发放所致。这些动作电位发放活动似乎激活了II - III层和V层锥体细胞中较慢的电导，从而产生N20。HFS监测可能有助于分别评估体感通路的皮层下和皮层成分的电生理情况。
