Iyengar P, Cody H S, Brogi E
Department of Pathology, Breast Service, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
Diagn Cytopathol. 2005 Dec;33(6):416-20. doi: 10.1002/dc.20364.
Pleomorphic adenoma of the breast (PAB) is a very rare neoplasm. Although quite unique in its morphology, PAB shares some similarities with adenomyoepithelioma and is considered by some authors as a variant of this entity. Cytologic diagnosis of this lesion can be very challenging, especially when limited sampling is available. The differential diagnosis of PAB includes metaplastic carcinoma. On cytologic material, fibroadenoma and phyllodes tumor should also be considered within the differential diagnosis. We report the findings in a case of PAB, initially misdiagnosed as mucinous carcinoma on fine-needle aspiration, and review the literature regarding this entity. Correct identification of this benign mammary neoplasm is important to avoid unnecessarily aggressive treatment.
乳腺多形性腺瘤（PAB）是一种非常罕见的肿瘤。尽管其形态颇为独特，但PAB与腺肌上皮瘤有一些相似之处，一些作者认为它是该实体的一种变体。对这种病变进行细胞学诊断可能极具挑战性，尤其是在样本有限的情况下。PAB的鉴别诊断包括化生性癌。在细胞学材料上，鉴别诊断还应考虑纤维腺瘤和叶状肿瘤。我们报告一例PAB病例的检查结果，该病例最初在细针穿刺时被误诊为黏液癌，并回顾了关于该实体的文献。正确识别这种良性乳腺肿瘤对于避免不必要的过度治疗很重要。
