基于cDNA微阵列的软组织肉瘤转化研究。
cDNA microarray-based translational research in soft tissue sarcoma.
作者信息
Lubieniecka Joanna M, Nielsen Torsten O
出版信息
J Surg Oncol. 2005 Dec 15;92(4):267-71. doi: 10.1002/jso.20409.
PMID:16299802
Abstract
The authors discuss application of cDNA microarray technology in translational research to identify diagnostic markers and therapeutic targets in adult soft tissue sarcoma. Recent results in synovial sarcoma are used to highlight the applicability of this technology for marker and target discovery, as well as the need for preclinical validation of putative therapeutic targets.
摘要
作者讨论了cDNA微阵列技术在转化研究中的应用，以识别成人软组织肉瘤中的诊断标志物和治疗靶点。滑膜肉瘤的最新研究结果被用于突出这项技术在标志物和靶点发现方面的适用性，以及对假定治疗靶点进行临床前验证的必要性。
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