Hugtenburg Jacqueline G, Heerdink Eibert R, Tso Yung Hwo
Utrecht Institute for Pharmaceutical Sciences, Department of Pharmacoepidemiology & Pharmacotherapy, Utrecht University, Utrecht, The Netherlands.
Acta Paediatr. 2005 Oct;94(10):1484-7. doi: 10.1111/j.1651-2227.2005.tb01824.x.
To gain more insight into the prescribing of psychoactive drugs by Dutch child psychiatrists.
A questionnaire was sent to all child psychiatrists in the Netherlands. Questions were asked about the prescribing of antidepressants, antipsychotics, anxiolytics and psychostimulants for psychiatric disorders in children.
The preference of specific antidepressants, antipsychotics and anxiolytics depends on the disorder. For different disorders, off-label prescribing varies from 19 to 71%.
Preferences differ widely. Off-label drug prescribing is high. More studies on the efficacy and safety of psychoactive drugs in children are therefore required.
更深入了解荷兰儿童精神科医生开具精神活性药物的情况。
向荷兰所有儿童精神科医生发送了一份调查问卷。询问了关于儿童精神疾病使用抗抑郁药、抗精神病药、抗焦虑药和精神兴奋剂的处方情况。
特定抗抑郁药、抗精神病药和抗焦虑药的偏好取决于疾病。对于不同的疾病,超说明书用药的比例在19%至71%之间。
偏好差异很大。超说明书用药情况很普遍。因此,需要更多关于精神活性药物在儿童中的疗效和安全性的研究。