Suzuki Kazumasa, Awata Shuichi, Suzuki Junpei, Iwasaki Hitoshi, Takano Takehisa, Matsuoka Hiroo
Department of Psychiatry, Tohoku University Hospital, Seiryo-machi, Sendai, Japan.
J ECT. 2005 Dec;21(4):251-2. doi: 10.1097/01.yct.0000182232.36998.33.
A 56-year-old married woman with late-onset Leonhard's confusion psychosis was treated successfully with acute electroconvulsive therapy (ECT) after failing to respond to antidepressants, neuroleptics, and benzodiazepines. Symptoms relapsed within 1 year despite the combined use of olanzapine and paroxetine. The patient responded to a second course of acute ECT, but a second relapse occurred within 3 months despite her use of olanzapine and paroxetine. The symptoms resolved with continuation ECT and lithium combined with paroxetine after response to a third course of acute ECT. To date, relapse has been prevented for 2 years. Continuation ECT and lithium combined with paroxetine after response to acute ECT may be effective in maintaining remission of Leonhard's confusion psychosis.
一名56岁已婚女性，患有迟发性莱昂哈德混淆性精神病，在对抗抑郁药、抗精神病药和苯二氮卓类药物治疗无效后，接受急性电休克治疗（ECT）获得成功。尽管联合使用了奥氮平和帕罗西汀，但症状在1年内复发。患者对第二个疗程的急性ECT有反应，但尽管使用了奥氮平和帕罗西汀，仍在3个月内再次复发。在对第三个疗程的急性ECT有反应后，持续ECT联合锂盐和帕罗西汀使症状得到缓解。迄今为止，已预防复发2年。急性ECT治疗有效后，持续ECT联合锂盐和帕罗西汀可能对维持莱昂哈德混淆性精神病的缓解有效。
