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电休克单一疗法治疗错乱性精神病:一种潜在的标准治疗方案?

Electroconvulsive monotherapy in confusion psychosis: a potential standard regimen?

作者信息

Neuhaus A H, Luborzewski A, Opgen-Rhein C, Jockers-Scherübl M C, Neu P

出版信息

Pharmacopsychiatry. 2007 Jul;40(4):170-1. doi: 10.1055/s-2007-981478.

DOI:10.1055/s-2007-981478
PMID:17694482
Abstract

We report on the successful use of continuation electroconvulsive therapy (ECT) as prophylactic treatment of relapse in a case of confusion psychosis. The 20-year-old patient exacerbated in an almost annual rhythm and had been characterized as pharmacologically treatment-resistant since he failed to respond to any psychopharmacological therapy including sufficient clozapine as well as mood-stabilizing and sedating pharmacological treatments. After the diagnosis of confusion psychosis, the patient received ECT as monotherapy and showed a marked reduction of symptoms. Continuation ECT was then conducted for 7 months after the patient was discharged from hospital. Two years later, our patient is still in remission while continuation ECT has been tapered; no prophylactic psychotropic medication was prescribed in the last 2 years. Implications of this case on the therapy of confusion psychosis as well as on the diagnostic classification of confusion psychosis within our current systems are discussed.

摘要

我们报告了连续电休克治疗(ECT)成功用于一例混淆性精神病复发预防性治疗的案例。该20岁患者几乎以每年一次的频率病情加重,自对包括足量氯氮平以及心境稳定剂和镇静药物治疗在内的任何精神药物治疗均无反应以来,其被判定为药物治疗抵抗。在诊断为混淆性精神病后,患者接受ECT单一治疗,症状显著减轻。患者出院后连续进行了7个月的ECT治疗。两年后,患者仍处于缓解期,ECT治疗已逐渐减量;过去两年未开具预防性精神药物。本文讨论了该病例对混淆性精神病治疗以及在我们当前系统中混淆性精神病诊断分类的意义。

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