Flores-Suarez L F
Immunology and rheumatology department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico.
Presse Med. 2005 Nov 19;34(20 Pt 1):1541-4. doi: 10.1016/s0755-4982(05)84220-4.
Antineutrophil cytoplasm autoantibodies (ANCA) are essential for the diagnosis of small-vessel vasculitis. Information for and against their usefulness to predict relapse exists. Different approaches, using various methods and definitions, have been used to answer the role of ANCA in predicting disease relapse. Multinational, multicentric prospective studies are needed to address this question using uniform definitions and preferably the best latest tools for ANCA detection.
抗中性粒细胞胞浆自身抗体(ANCA)对于小血管炎的诊断至关重要。关于其预测复发是否有用的支持和反对信息均存在。已经采用了不同的方法,使用各种手段和定义来回答ANCA在预测疾病复发中的作用。需要开展多国、多中心前瞻性研究,使用统一的定义,并最好采用检测ANCA的最佳最新工具来解决这个问题。