一种疗法剖析：非依从性使用期间对多用途溶液的考量

Anatomy of a regimen: consideration of multipurpose solutions during non-compliant use.

作者信息

Rosenthal Ruth A, Henry Cindy L, Stone Ralph P, Schlech Barry A

机构信息

Alcon Research Ltd., 6201 S. Freeway, Fort Worth, TX 76134-2099, USA.

出版信息

Cont Lens Anterior Eye. 2003 Mar;26(1):17-26. doi: 10.1016/S1367-0484(02)00085-1.

DOI:10.1016/S1367-0484(02)00085-1

PMID:16303493

Abstract

Consumers are often non-compliant with instructions for contact lens care products. This study explores the antimicrobial capacity of multipurpose solutions using variable use conditions. Opti-Free Express (Alcon) Multi-Purpose Disinfecting Solution with Polyquad (Alcon) and Aldox (Alcon) antimicrobial system and products containing PHMB (ReNu MultiPlus, Solo-care, and Complete multipurpose solutions) were evaluated. Products were challenged with Fusarium solani, Candida albicans, Serratia marcescens, Pseudomonas aeruginosa, and Staphylococcus aureus. The antimicrobial activity and effectiveness of regimen steps, rinse volume, stored lenses and organic soil were evaluated. The results show that products using similar regimens can show different disinfection abilities. Opti-Free Express Multi-Purpose Disinfecting Solution retained effectiveness using variable and non-compliant conditions.

摘要

消费者往往不遵守隐形眼镜护理产品的使用说明。本研究探讨了在不同使用条件下多功能护理液的抗菌能力。对含有Polyquad（爱尔康）和Aldox（爱尔康）抗菌系统的Opti-Free Express（爱尔康）多功能消毒护理液以及含有聚六亚甲基双胍（PHMB）的产品（ReNu MultiPlus、Solo-care和Complete多功能护理液）进行了评估。用茄病镰刀菌、白色念珠菌、粘质沙雷氏菌、铜绿假单胞菌和金黄色葡萄球菌对产品进行挑战。评估了护理步骤、冲洗量、储存镜片和有机污垢的抗菌活性和效果。结果表明，使用相似护理方案的产品可能表现出不同的消毒能力。Opti-Free Express多功能消毒护理液在不同和不规范条件下仍保持有效性。