进化：人类和黑猩猩进化过程中的自然选择。

Evolution: natural selection in the evolution of humans and chimps.

作者信息

Ellegren Hans

机构信息

Department of Evolutionary Biology, Uppsala University, Sweden.

出版信息

Curr Biol. 2005 Nov 22;15(22):R919-22. doi: 10.1016/j.cub.2005.10.060.

DOI:10.1016/j.cub.2005.10.060

PMID:16303548

Abstract

We now have more or less full sequences of both human and chimp genomes, allowing comparison that sheds light on their evolution. A few hundred genes show significant evidence for adaptive evolution in the two lineages, but the actual number might be much higher. Natural selection has eliminated about 75% of amino acid changes in coding sequence since the split of the human and chimpanzee genomes.

摘要

我们现在或多或少已经掌握了人类和黑猩猩基因组的完整序列，这使得我们能够进行比较，从而揭示它们的进化历程。几百个基因显示出在这两个谱系中存在适应性进化的显著证据，但实际数量可能要高得多。自人类和黑猩猩基因组分化以来，自然选择已经消除了编码序列中约75%的氨基酸变化。