Hashimoto M, Sugitani I, Inaba H, Sakamoto H, Shibayama K, Go D, Kitamura S
Department of Surgery, Social Health Insurance Medical Center, Tokyo, Japan.
Nihon Geka Gakkai Zasshi. 1992 Jun;93(6):654-6.
We reported a case of anaplastic carcinoma of mediastinal goiter. The initial symptom was hoarseness, and thyroid scintigram and venogram revealed mediastinal thyroid malignant tumor, although cervical tumor could not be palpated. Operation was performed with median sternotomy. The size of the tumor was 8 x 6 x 3cm. Histological examination showed papillary adenocarcinoma of left lower pole of the thyroid gland which was transformed into anaplastic carcinoma and extended to the mediastinal cavity. Anaplastic carcinoma of mediastinal goiter is very rare, and our case showed anaplastic transformation from papillary adenocarcinoma.
我们报告了一例纵隔甲状腺肿间变性癌。最初症状为声音嘶哑,甲状腺闪烁扫描和静脉造影显示纵隔甲状腺恶性肿瘤,尽管未触及颈部肿瘤。通过正中胸骨切开术进行手术。肿瘤大小为8×6×3厘米。组织学检查显示甲状腺左下极乳头状腺癌已转变为间变性癌并延伸至纵隔腔。纵隔甲状腺肿间变性癌非常罕见,我们的病例显示由乳头状腺癌发生间变性转变。