Guzowski Magdalena, Tumuluri Krishna, Walker D M, Maloof Anthony
Department of Ophthalmology, Westmead Hospital, Westmead, Australia.
Ophthalmic Plast Reconstr Surg. 2005 Nov;21(6):449-51. doi: 10.1097/01.iop.0000182303.15085.3b.
A 54-year-old man presented with a painful left proptosis and a soft tissue mass at the inferolateral aspect of the left orbit with bone involvement. There was no clinical or investigational evidence of systemic disease. Both light microscopy and immunohistochemistry were required for the diagnosis of Ewing sarcoma. After failure of chemotherapy alone, management included extensive surgical excision and postoperative adjuvant radiotherapy and chemotherapy. Despite intervention, the patient died of widespread metastatic disease 17 months after initial presentation. Although rare, Ewing sarcoma should be included in the differential diagnosis of uniform round cell orbital tumors in adults.
一名54岁男性患者，出现左侧眼眶疼痛性眼球突出，左眼眶外下侧有一软组织肿块，伴有骨质受累。无全身性疾病的临床或检查证据。尤因肉瘤的诊断需要光镜检查和免疫组织化学检查。单纯化疗失败后，治疗包括广泛手术切除及术后辅助放疗和化疗。尽管进行了干预，患者在初次就诊17个月后死于广泛转移性疾病。尽管罕见，但尤因肉瘤应纳入成人均匀圆形细胞眼眶肿瘤的鉴别诊断。
