Maguiness Sheilagh, Balma-Mena Alexandra, Pope Elena, Weinstein Miriam
University of California at San Francisco, USA.
Clin Pediatr (Phila). 2010 Nov;49(11):1033-7. doi: 10.1177/0009922810374977. Epub 2010 Aug 19.
Henoch-Schönlein purpura (HSP) is the most common vasculitis occurring in childhood. Clinical presentation involves the classic tetrad of abdominal pain, nonthrombocytopenic purpura, arthritis, and renal involvement. Dermatological manifestations of HSP are characteristic of the condition and consist of palpable purpura and edema of the lower extremities and buttocks. The clinical spectrum of HSP is highly variable; however, vesicles and bullae have rarely been reported as the presenting feature. To date, there are 14 case reports of bullous HSP in the literature in English. The authors report 6 additional cases of bullous HSP, including a recurrent case, presenting to the Hospital for Sick Children in Toronto, Canada.
过敏性紫癜（HSP）是儿童期最常见的血管炎。临床表现包括腹痛、非血小板减少性紫癜、关节炎和肾脏受累这一典型四联征。HSP的皮肤表现具有该病的特征，包括可触及的紫癜以及下肢和臀部水肿。HSP的临床谱变化很大；然而，水疱和大疱很少被报道为首发特征。迄今为止，英文文献中有14例大疱性HSP的病例报告。作者报告了另外6例大疱性HSP病例，包括1例复发病例，这些病例均来自加拿大多伦多病童医院。
