胎儿生物物理评分在胎膜早破治疗中的应用价值
[Usefulness of fetal biophysical profile in preterm rupture of membranes with treatment].
作者信息
Romero Arauz Juan Fernando, Martínez Chéquer Juan Carlos, Alonso López Angel García, Jurado Hernández Víctor Hugo, Ayala Méndez José Antonio
机构信息
Departamento de Medicina Perinatal, Hospital de Ginecología y Obstetricia Luis Castelazo Ayala, Instituto Mexicano del Seguro Social, México, DF.
出版信息
Ginecol Obstet Mex. 2005 Aug;73(8):415-23.
OBJECTIVE
To evaluate the usefulness of the fetal biophysical profile as a predictor of early neonatal infection in patients with preterm rupture of membranes in conservative management.
PATIENTS AND METHODS
This is a validation study of a diagnostic test. Between November, 2001 and August, 2003, 75 patients with 27 to 33 weeks of gestation and preterm rupture of membranes in conservative management were studied. Daily, a fetal biophysical profile was applied to them. Statistical analysis was done with chi square test and with a 2 x 2 contingency table that compared the biophysical score of + 8 and < or = 6 versus the presence or absence of early neonatal infection.
RESULTS
The biophysical score < or = 6 was associated with early neonatal infection (p < 0.05), with sensitivity, specificity, positive and negative predictive values of 80, 85, 64 and 85%, respectively (OR 9.73, 95% CI: 2.88-34.63; p = 0.0000164).
CONCLUSIONS
The biophysical score < or = 6 was significantly associated with early neonatal infection.
目的
评估胎儿生物物理评分作为胎膜早破保守治疗患者早期新生儿感染预测指标的有效性。
患者与方法
这是一项诊断试验的验证性研究。2001年11月至2003年8月期间，对75例孕周为27至33周且胎膜早破并接受保守治疗的患者进行了研究。每天对他们进行胎儿生物物理评分。采用卡方检验和2×2列联表进行统计分析，比较生物物理评分为+8和≤6与早期新生儿感染的有无。
结果
生物物理评分≤6与早期新生儿感染相关（p<0.05），其敏感性、特异性、阳性预测值和阴性预测值分别为80%、85%、64%和85%（比值比9.73，95%可信区间：2.88 - 34.63；p = 0.0000164）。
结论
生物物理评分≤6与早期新生儿感染显著相关。
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