Crystallization and preliminary X-ray diffraction studies of two myotoxic Lys49-phospholipases A2 complexed with alpha-tocopherol.

Suppr

超能文献

作者信息

dos Santos Juliana I, Takeda Agnes A S, Marchi-Salvador Daniela P, Soares Andreimar M, Fontes Marcos R M

机构信息

Departamento de Física e Biofísica, Instituto de Biociências, UNESP, C. P. 510, CEP 18618-000, Botucatu-SP, Brazil.

出版信息

Protein Pept Lett. 2005 Nov;12(8):819-22. doi: 10.2174/0929866054864283.

DOI:10.2174/0929866054864283

PMID:16305555

Abstract

BnSP-7 and BnSP-6, two Lys49-phospholipase A2 isolated from Bothrops neuwiedi pauloensis snake venom, were co-crystallized with alpha-tocopherol and X-ray diffraction data were collected for both complexes (2.2 and 2.6 A). A new "alternative" quaternary conformation for these two complexes compared with all other dimeric Lys49-PLA2 has been observed.

摘要

相似文献

Crystallization and preliminary X-ray diffraction studies of two myotoxic Lys49-phospholipases A2 complexed with alpha-tocopherol.

Protein Pept Lett. 2005 Nov;12(8):819-22. doi: 10.2174/0929866054864283.

Structural and functional characterization of BnSP-7, a Lys49 myotoxic phospholipase A(2) homologue from Bothrops neuwiedi pauloensis venom.

Arch Biochem Biophys. 2000 Jun 15;378(2):201-9. doi: 10.1006/abbi.2000.1790.

Crystallization of the Lys49 PLA2 homologue, myotoxin II, from the venom of Atropoides nummifer.

Biochim Biophys Acta. 2004 Dec 1;1703(1):87-9. doi: 10.1016/j.bbapap.2004.09.006.

Crystallization and preliminary X-ray diffraction analysis of myotoxin I, a Lys49-phospholipase A2 from Bothrops moojeni.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Oct 1;61(Pt 10):882-4. doi: 10.1107/S174430910502717X. Epub 2005 Sep 13.

Crystallization and preliminary X-ray diffraction analysis of a myotoxic Lys49-PLA2 from Bothrops jararacussu venom complexed with p-bromophenacyl bromide.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt 6):600-3. doi: 10.1107/S174430910601801X. Epub 2006 May 31.

Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A(2): quaternary structure and inhibition mechanism insights.

Biochem Biophys Res Commun. 2003 Nov 21;311(3):713-20. doi: 10.1016/j.bbrc.2003.10.047.

Crystallization of bothropstoxin II isolated from the venom of Bothrops jararacussu.

Toxicon. 1996 May;34(5):614-7. doi: 10.1016/0041-0101(95)00143-3.

Crystallization and preliminary X-ray diffraction analysis of suramin, a highly charged polysulfonated napthylurea, complexed with a myotoxic PLA2 from Bothrops asper venom.

Biochim Biophys Acta. 2004 Dec 1;1703(1):83-5. doi: 10.1016/j.bbapap.2004.08.009.

Crystallization and preliminary X-ray diffraction analysis of a myotoxic phospholipase A(2) homologue from Bothrops neuwiedi pauloensis venom.

Biochim Biophys Acta. 1999 Jul 13;1432(2):393-5. doi: 10.1016/s0167-4838(99)00120-x.

Preliminary X-ray crystallographic studies of a Lys49-phospholipase A2 homologue from Bothrops pirajai venom complexed with p-bromo-phenacyl bromide and alpha-tocopherol inhibitors.

Protein Pept Lett. 2007;14(7):698-701. doi: 10.2174/092986607781483796.

引用本文的文献

Therapeutic application of natural inhibitors against snake venom phospholipase A(2).

Bioinformation. 2012;8(1):48-57. doi: 10.6026/97320630008048. Epub 2012 Jan 6.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验