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剑突下与电视胸腔镜心包“开窗术”的对比研究

Comparative study of subxiphoid versus video-thoracoscopic pericardial "window".

作者信息

O'Brien Patrick K H, Kucharczuk John C, Marshall M Blair, Friedberg Joseph S, Chen Zhen, Kaiser Larry R, Shrager Joseph B

机构信息

Section of General Thoracic Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

出版信息

Ann Thorac Surg. 2005 Dec;80(6):2013-9. doi: 10.1016/j.athoracsur.2005.05.059.

Abstract

BACKGROUND

It remains undefined whether surgical subxiphoid drainage or thoracoscopic pericardial "window" is the optimal operative approach to pericardial effusion. We hypothesized that the true window into the pleural space created by the latter might improve the duration of freedom from recurrent effusion.

METHODS

We conducted a retrospective chart review of indications, preoperative and intraoperative variables, morbidity, recurrence, and survival.

RESULTS

Fifty-six patients underwent the subxiphoid procedure and 15 underwent the thoracoscopic procedure. Echocardiographic evidence of tamponade was present before 8 of 10 thoracoscopic procedures (80%) and 43 of 56 subxiphoid procedures (81%) for which descriptions of hemodynamics were available. In addition, non-pericardial procedures were performed in 10 (67%) and 18 (32%) patients, respectively (p = 0.020). Anesthesia time was longer at thoracoscopy (117.1 +/- 32.4 vs 81.1 +/- 25.5 minutes; p < 0.001). Procedural morbidity was higher after thoracoscopy (4 [27%] vs 1 [2%]; p = 0.006), but was generally minor. Hospital mortality tended to be higher after the subxiphoid procedure (7 [13%] vs 0 [0%]; p = 0.332), but none of the deaths was procedure-related. Follow-up was complete for 65 patients (92%). Recurrence occurred in 1 thoracoscopy patient (8%) and 5 subxiphoid patients (10%) (p = 1.000). Mean time to recurrence by Kaplan-Meier analysis trends were longer after thoracoscopy (36.1 vs 11.4 months; p = 0.16), and multivariate analysis identified the thoracoscopic approach as an independent predictor of freedom from recurrence (relative risk, 0.41; p = 0.014).

CONCLUSIONS

Operative time and minor procedural morbidity are higher with thoracoscopic pericardial window, but long-term control of effusion seemed to be better than after subxiphoid surgical drainage.

摘要

背景

目前尚不清楚剑突下手术引流或胸腔镜心包“开窗”术是否是心包积液的最佳手术方法。我们推测,后者所形成的真正进入胸膜腔的窗口可能会延长无复发性积液的时间。

方法

我们对适应症、术前和术中变量、发病率、复发率和生存率进行了回顾性图表审查。

结果

56例患者接受了剑突下手术,15例接受了胸腔镜手术。在10例胸腔镜手术中的8例(80%)和56例剑突下手术中的43例(81%)(可获得血流动力学描述)术前存在心包填塞的超声心动图证据。此外,分别有10例(67%)和18例(32%)患者进行了非心包手术(p = 0.020)。胸腔镜检查时麻醉时间更长(117.1±32.4分钟对81.1±25.5分钟;p < 0.001)。胸腔镜检查后手术发病率更高(4例[27%]对1例[2%];p = 0.006),但一般较轻。剑突下手术后医院死亡率往往更高(7例[13%]对0例[0%];p = 0.332),但所有死亡均与手术无关。65例患者(92%)完成了随访。1例胸腔镜手术患者(8%)和5例剑突下手术患者(10%)出现复发(p = 1.000)。通过Kaplan-Meier分析,胸腔镜检查后复发的平均时间趋势更长(36.1个月对11.4个月;p = 0.16),多变量分析确定胸腔镜手术方法是无复发的独立预测因素(相对风险,0.41;p = 0.014)。

结论

胸腔镜心包开窗术的手术时间和轻微手术发病率较高,但积液的长期控制似乎优于剑突下手术引流。

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