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[辐射所致心脏毒性。2例临床病例描述]

[Cardiotoxicity caused by radiation. Description of 2 clinical cases].

作者信息

Cucchi G

机构信息

Divisione di Cardiologia e UCIC, USSL n. 22, Sondrio.

出版信息

Minerva Med. 1992 Jun;83(6):385-7.

PMID:1630701
Abstract

The paper reports two cases of valvular cardiac lesions and pericardial effusion caused by radiation. The widespread use of radiotherapy makes this a highly relevant problem. Radiation most frequently causes damage to the pericardium leading to pericardial effusion, and in some cases provokes myocardial, valvular and coronary lesions and even myocardial infarction. Cardiotoxicity depends on the radiation dose which must generally exceed 40 Gy. Radiated patients must be carefully monitored so as to diagnose cardiac lesions at an early stage. The ongoing improvement of radiotherapy techniques is the best means of preventing cardiac damage due to radiotherapy.

摘要

该论文报告了两例由辐射引起的心脏瓣膜病变和心包积液的病例。放射治疗的广泛应用使这成为一个高度相关的问题。辐射最常导致心包损伤,进而引起心包积液,在某些情况下还会引发心肌、瓣膜和冠状动脉病变,甚至心肌梗死。心脏毒性取决于辐射剂量,一般必须超过40 Gy。必须对接受放疗的患者进行仔细监测,以便早期诊断心脏病变。放疗技术的不断改进是预防放疗所致心脏损伤的最佳方法。

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