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Onchocerciasis-related epilepsy? Prospects at a time of uncertainty.

作者信息

Marin Benoît, Boussinesq Michel, Druet-Cabanac Michel, Kamgno Joseph, Bouteille Bernard, Preux Pierre-Marie

机构信息

Institut de Neuroépidémiologie et de Neurologie Tropicale (EA 3174), Faculté de Médecine, 2 rue de Docteur Marcland, 87025 Limoges Cedex, France.

出版信息

Trends Parasitol. 2006 Jan;22(1):17-20. doi: 10.1016/j.pt.2005.11.006. Epub 2005 Nov 22.

DOI:10.1016/j.pt.2005.11.006
PMID:16307906
Abstract

Epilepsy and onchocerciasis (river blindness) constitute serious public health problems in several tropical countries. There are four main mechanisms that might explain a relationship between these two diseases: (i) the presence of Onchocerca volvulus in the central nervous system; (ii) the pathogenicity of various O. volvulus strains; (iii) immunological mechanisms involving cross-reactive immunization or cytokine production during infection; and (iv) the triggering role of insomnia due to itching.

摘要

相似文献

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Onchocerciasis-related epilepsy? Prospects at a time of uncertainty.
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2
Distribution of the blinding and nonblinding strains of Onchocerca volvulus in Nigeria.盘尾丝虫致盲和非致盲菌株在尼日利亚的分布情况。
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Review of epidemiological studies searching for a relationship between onchocerciasis and epilepsy.关于寻找盘尾丝虫病与癫痫之间关系的流行病学研究综述。
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Immunopathogenesis of Onchocerca volvulus keratitis (river blindness): a novel role for endosymbiotic Wolbachia bacteria.盘尾丝虫性角膜炎（河盲症）的免疫发病机制：内共生沃尔巴克氏体细菌的新作用
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Infectious disease. New culprit emerges in river blindness.传染病。河盲症出现新的致病源。
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Wolbachia endosymbiont levels in severe and mild strains of Onchocerca volvulus.旋盘尾丝虫重度和轻度菌株中的沃尔巴克氏体共生菌水平。
Mol Biochem Parasitol. 2005 May;141(1):109-12. doi: 10.1016/j.molbiopara.2005.02.006.
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Onchocerca volvulus: limited heterogeneity in the nuclear and mitochondrial genomes.旋盘尾丝虫：核基因组和线粒体基因组中的有限异质性
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Could antibiotics cure river blindness?抗生素能治愈河盲症吗？
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Immunopathogenesis of Onchocerca volvulus keratitis (river blindness): a novel role for TLR4 and endosymbiotic Wolbachia bacteria.盘尾丝虫性角膜炎（河盲症）的免疫发病机制：Toll样受体4和内共生沃尔巴克氏体细菌的新作用
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Immune-mediated Onchocerca volvulus sclerosing keratitis in the mouse.
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