Davies H D, Jones E L, Sheng R Y, Leslie B, Matlow A G, Gold R
Division of Infectious Diseases, Hospital for Sick Children, Toronto, Ontario, Canada.
Pediatr Infect Dis J. 1992 May;11(5):349-54. doi: 10.1097/00006454-199205000-00002.
Although the epidemiology of nosocomial urinary tract infections (NUTIs) is well-described in the adult population, there is little information on children. We therefore reviewed all our patients with NUTIs, to determine their age, underlying diagnoses, microorganisms involved, use of catheters and secondary bacteremias. During a 2-year period at our institution, NUTIs accounted for 10% of all nosocomial infections (0.8 infections/100 admissions). Of 44,948 patients admitted during this period 0.7% (n = 318) acquired 351 episodes of NUTI. The patient ages ranged from 5 days to 21 years. The highest rates of NUTIs per ward (NUTI/100 admissions or transfers to the ward) were seen in the neonatal surgery (4.8), hematology/oncology (2.7), infant neurosurgery (2.1) and neonatal intensive care units (1.9). The most common organisms isolated were Escherichia coli (26%), Enterococcus sp. (15%), Pseudomonas sp. (13%), Klebsiella sp. (10%) and coagulase-negative Staphylococcus (9%). Catheterrelated infections accounted for 48% of all the NUTIs. Secondary bacteremia occurred rarely, with an incidence of 2.9% (n = 7). We conclude that NUTIs represent an important proportion (10%) of nosocomial infections in our population of hospitalized children, but secondary bacteremia is uncommon.
虽然医院获得性尿路感染（NUTIs）的流行病学在成人中已有详尽描述，但关于儿童的信息却很少。因此，我们回顾了所有患有医院获得性尿路感染的患者，以确定他们的年龄、潜在诊断、所涉及的微生物、导管使用情况和继发性菌血症。在我们机构的两年时间里，医院获得性尿路感染占所有医院感染的10%（0.8例感染/100次入院）。在此期间收治的44948例患者中，0.7%（n = 318）发生了351次医院获得性尿路感染。患者年龄从5天到21岁不等。每个病房医院获得性尿路感染的最高发生率（医院获得性尿路感染/100次入院或转入该病房的次数）见于新生儿外科（4.8）、血液学/肿瘤学（2.7）、婴儿神经外科（2.1）和新生儿重症监护病房（1.9）。分离出的最常见微生物为大肠埃希菌（26%）、肠球菌属（15%）、假单胞菌属（13%）、克雷伯菌属（10%）和凝固酶阴性葡萄球菌（9%）。与导管相关的感染占所有医院获得性尿路感染的48%。继发性菌血症很少发生，发生率为2.9%（n = 7）。我们得出结论，在我们住院儿童人群中，医院获得性尿路感染占医院感染的重要比例（10%），但继发性菌血症并不常见。
