Dauchy F A, Vincendeau P, Lifermann F
Service de médecine interne C, service du Docteur-Lifermann, centre hospitalier de Dax, boulevard Yves-Du-Manoir, 40100 Dax, France.
Med Mal Infect. 2006 Jan;36(1):42-6. doi: 10.1016/j.medmal.2005.10.005. Epub 2005 Nov 23.
Fascioliasis is a parasitic infection caused by the ingestion of food contaminated with Fasciola hepatica.
We report an epidemic of eight cases of fascioliasis in southern France, and describe the clinical features, and the diagnostic and therapeutic tools.
Our series includes almost every clinical form described, apart from the pseudotumoral form. Early diagnosis relied mainly on serum assays. Among these, counter-electrophoresis was the first to be positive and therefore appears to be the most useful test, including cases where patients are asymptomatic or mildly ill. Patients were treated with the usual dose of triclabendazole, but six of them required a double dose to recover.
The use of 20 mg/kg triclabendazole is safe and efficient for patients with acute fascioliasis when a single dose has failed to cure them.
肝片吸虫病是一种因摄入被肝片吸虫污染的食物而引起的寄生虫感染。
我们报告了法国南部8例肝片吸虫病的流行情况，并描述了其临床特征以及诊断和治疗方法。
除假瘤型外，我们的病例系列几乎涵盖了所有已描述的临床类型。早期诊断主要依靠血清检测。其中，对流免疫电泳最先呈阳性，因此似乎是最有用的检测方法，包括患者无症状或病情较轻的情况。患者接受了常规剂量的三氯苯达唑治疗，但其中6人需要双倍剂量才能康复。
当单剂量20mg/kg三氯苯达唑未能治愈急性肝片吸虫病患者时，使用该剂量是安全有效的。
