Villanova N, Pasqui F, Burzacchini S, Forlani G, Manini R, Suppini A, Melchionda N, Marchesini G
Department Internal Medicine and Gastroenterology, Unit of Metabolic Diseases, Alma Mater Studiorum University of Bologna, Bologna, Italy.
Int J Obes (Lond). 2006 Apr;30(4):697-703. doi: 10.1038/sj.ijo.0803185.
To investigate the effects of a specific program to implement physical activity (fitness program) on weight loss maintenance, activity level and resting energy expenditure (REE).
Observational study of subjects completing a behavioral program.
In total, 200 overweight/obese subjects (36 males, aged 20-66 years; average BMI, 35.2 kg/m2). Program and measurements:The fitness program consisted of 12 bimonthly sessions, chaired by doctors and dietitians, involving groups of 8-12 subjects. Patients entered the program approximately 9 months after the end of behavioral treatment, during a weight loss maintenance period. The goal was set at a light-to-moderate daily physical activity (brisk walking), quantitatively measured by a pedometer; REE was measured before and after the fitness program by indirect calorimetry in a subset of patients.
The fitness program restarted the process of weight loss in over 60% of subjects. At the end of the study, 84% of patients walked at least 5000 steps per day, compared with 24% at the beginning of the study. The probability of losing from 5 to 10% of initial body weight increased by 20% for any 1000 steps/day (OR, 1.20; 95% CI (confidence interval), 1.07-1.35), and that of losing more than 10% by over 30% (OR, 1.33; 95% CI, 1.19-1.49). REE increased significantly by 100 kcal/day (+7.5%), in spite of further weight loss (-1.8%).
A specific fitness program in the weight maintenance phase after a behavioral program may significantly improve the long-term control of obesity.
研究一项实施体育活动的特定计划(健身计划)对体重维持、活动水平和静息能量消耗(REE)的影响。
对完成一项行为计划的受试者进行观察性研究。
总共200名超重/肥胖受试者(36名男性,年龄20 - 66岁;平均BMI为35.2kg/m²)。计划与测量:健身计划包括由医生和营养师主持的12次双月课程,每组8 - 12名受试者。患者在行为治疗结束后约9个月进入该计划,处于体重维持期。目标设定为轻度至中度的日常体育活动(快走),通过计步器进行定量测量;在一部分患者中,通过间接测热法在健身计划前后测量REE。
健身计划使超过60%的受试者重新开始体重减轻过程。在研究结束时,84%的患者每天至少走5000步,而研究开始时这一比例为24%。每天每多走1000步,体重减轻初始体重的5%至10%的概率增加20%(比值比[OR],1.20;95%置信区间[CI],1.07 - 1.35),体重减轻超过10%的概率增加超过30%(OR,1.33;95%CI,1.19 - 1.49)。尽管体重进一步减轻(-1.8%),REE仍显著增加100千卡/天(+7.5%)。
行为计划后的体重维持阶段的特定健身计划可能显著改善肥胖的长期控制。