Gao Ning, Hu Long-ji, Xie Li-xin, Guo Dian-qiang
Qingdao Eye Hospital, Shandong Eye Institute, Qingdao 266071, China.
Zhonghua Yan Ke Za Zhi. 2005 Nov;41(11):966-71.
To evaluate the effects of laser in situ keratomileusis (LASIK) and laser-assisted subepithelial keratomileusis (LASEK) on wavefront aberration for treatment of myopia.
Eighteen right eyes with LASIK and 18 right eyes with LASEK were included in this study. The patients were selected randomly for evaluation of the wavefront aberration using a WFA1000 subjective aberrometer before and 10 days, 1 and 3 months after treatment. The coefficient of 35 terms of zenike was obtained by aberrometer, and root mean square (RMS) of each and total high order aberration was calculated by Matlab5.3. SPSS10.0 was used for statistical analysis.
Uncorrected visual acuity in all eyes after operation achieved or exceeded preoperative best corrected visual acuity; no serious complication occurred to threaten visual acuity. RMS of each and total high order aberration was increased at 10 days after LASIK, and then decreased at 1 and 3 months, during which period the changes after LASEK were the same as those after LASIK, only smaller than that of the preoperative data except order 3. Statistical difference of order 3, 4 and total high order before and 10 days after LASIK was significant, while that 1 and 3 months was insignificant. There was statistically significant difference of each and total high order before and after LASEK, whereas, the results of LASEK showed no significant difference when compared with that of LASIK.
RMS of wavefront aberration increased rapidly at 10 days after LASIK and LASEK and decreased gradually at 1 and 3 months. There was no statistically significant difference in RMS at 1 and 3 months after treatment. The degree of crease after LASEK is smaller than that after LASIK.
评估准分子原位角膜磨镶术(LASIK)和准分子激光上皮下角膜磨镶术(LASEK)治疗近视对波前像差的影响。
本研究纳入18例行LASIK的右眼和18例行LASEK的右眼。随机选取患者,于治疗前、治疗后10天、1个月和3个月使用WFA1000主观像差仪评估波前像差。通过像差仪获得35项泽尼克系数,并用Matlab5.3计算各项及总高阶像差的均方根(RMS)。采用SPSS10.0进行统计分析。
所有术眼术后裸眼视力均达到或超过术前最佳矫正视力;未发生严重并发症威胁视力。LASIK术后10天各项及总高阶像差的RMS增加,之后在1个月和3个月时下降,在此期间LASEK术后的变化与LASIK术后相同,仅除3阶外均小于术前数据。LASIK术前与术后10天3阶、4阶及总高阶像差的统计差异有显著性,而术后1个月和3个月无显著性。LASEK术前与术后各项及总高阶像差有统计学显著性差异,然而,与LASIK相比,LASEK的结果无显著性差异。
LASIK和LASEK术后10天波前像差的RMS迅速增加,1个月和3个月时逐渐下降。治疗后1个月和3个月RMS无统计学显著性差异。LASEK术后褶皱程度小于LASIK术后。