Tobaigy Faisal M, Ghanem Ramon C, Sayegh Rony R, Hallak Joelle A, Azar Dimitri T
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.
Am J Ophthalmol. 2006 Dec;142(6):901-8. doi: 10.1016/j.ajo.2006.08.001. Epub 2006 Sep 8.
To compare the visual and refractive outcomes of laser epithelial keratomileusis (LASEK) and laser in situ keratomileusis (LASIK) for the treatment of low to moderate myopia.
Retrospective, nonrandomized, control-matched study.
The charts of 2257 eyes that underwent LASEK or LASIK treatment were reviewed. Patients who were 21 years of age or older having between -0.75 and -6.00 diopters (D) of myopia with up to -2.25 D of astigmatism were included. One hundred twenty-two LASEK-treated eyes were matched with 122 LASIK-treated eyes having preoperative spheres, cylinders, and spherical equivalent (SE) within +/-0.50 D. Both groups had similar preoperative best spectacle-corrected visual acuity (BSCVA), laser platform, and follow-up durations. Outcome measures were visual and refractive results.
Preoperatively, the mean SE was -3.50 +/- 1.40 D for LASEK and -3.50 +/- 1.42 D for LASIK (P = .59). Postoperatively, the mean logarithm of minimum angle of resolution (logMAR) uncorrected visual acuity (UCVA) was 0.01 +/- 0.08 (20/21) for LASEK and 0.06 +/- 0.12 (20/23) for LASIK; the mean SE was -0.15 +/- 0.40 D for LASEK and -0.37 +/- 0.45 D for LASIK; and the mean logMAR of BSCVA was -0.03 +/- 0.06 (20/19) for LASEK and -0.02 +/- 0.05 (20/19) for LASIK. No eye lost 2 or more lines of BSCVA in both groups.
Slight differences in the visual and refractive results between LASEK and LASIK were observed, despite the use of the same nomogram. Both procedures were safe, effective, and predictable. Nomogram adjustment may be necessary for LASIK surgeons adopting surface ablation.
比较准分子激光上皮下角膜磨镶术(LASEK)和准分子激光原位角膜磨镶术(LASIK)治疗中低度近视的视力和屈光效果。
回顾性、非随机、对照匹配研究。
回顾了2257只接受LASEK或LASIK治疗的眼睛的病历。纳入年龄在21岁及以上、近视度数在-0.75至-6.00屈光度(D)之间且散光度数最高为-2.25 D的患者。122只接受LASEK治疗的眼睛与122只接受LASIK治疗的眼睛进行匹配,这些眼睛术前的球镜、柱镜和等效球镜(SE)在±0.50 D以内。两组患者术前最佳矫正视力(BSCVA)、激光平台和随访时间相似。观察指标为视力和屈光结果。
术前,LASEK组的平均SE为-3.50±1.40 D,LASIK组为-3.50±1.42 D(P = 0.59)。术后,LASEK组未矫正视力(UCVA)的平均最小分辨角对数(logMAR)为0.01±0.08(20/21),LASIK组为0.06±0.12(20/23);LASEK组的平均SE为-0.15±0.40 D,LASIK组为-0.37±0.45 D;LASEK组BSCVA的平均logMAR为-0.03±0.06(20/19),LASIK组为-0.02±0.05(20/19)。两组均无眼睛的BSCVA下降2行或更多行。
尽管使用相同的列线图,但观察到LASEK和LASIK在视力和屈光结果上存在细微差异。两种手术均安全、有效且可预测。采用表面切削术的LASIK手术医生可能需要调整列线图。