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有妊娠期糖尿病病史的女性产后糖尿病筛查

Postpartum diabetes screening in women with a history of gestational diabetes.

作者信息

Smirnakis Karen V, Chasan-Taber Lisa, Wolf Myles, Markenson Glenn, Ecker Jeffrey L, Thadhani Ravi

机构信息

Renal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

出版信息

Obstet Gynecol. 2005 Dec;106(6):1297-303. doi: 10.1097/01.AOG.0000189081.46925.90.

Abstract

OBJECTIVE

Women with a history of gestational diabetes mellitus (GDM) are at high risk for developing type 2 diabetes (diabetes mellitus, DM). The American Diabetes Association recommends regular postpartum diabetes screening for women with a history of GDM, but the American College of Obstetricians and Gynecologists (ACOG) is not as directive. We sought to examine postpartum glycemic testing in women diagnosed with GDM.

METHODS

We conducted an observational cohort study of women diagnosed with GDM at one of two large academic medical centers between 2000 and 2001. Kaplan-Meier estimates of the time from delivery to the first postpartum DM screening tests were determined, and predictors of postpartum DM screening were examined using Cox proportional hazards testing.

RESULTS

Only 37% of eligible women underwent the postpartum diabetes screening tests recommended by the American Diabetes Association (fasting glucose or oral glucose tolerance test [OGTT]), with a median time from delivery to the first such testing of 428 days. By comparison, 94% of women underwent postpartum cervical cancer screening using a Papanicolaou (Pap) test, with a median time from delivery to Pap testing of 49 days. Even when random glucose testing was included in a broad definition of postpartum DM screening (random or fasting glucose, glycosylated hemoglobin, or OGTT), only two thirds of women (67%) received a postpartum glycemic assessment.

CONCLUSION

In the population studied, only 37% of women with a history of GDM were screened for postpartum DM according to guidelines published by the American Diabetes Association. Efforts to improve postpartum DM screening in this high-risk group are warranted.

摘要

目的

有妊娠期糖尿病(GDM)病史的女性患2型糖尿病(糖尿病,DM)的风险很高。美国糖尿病协会建议对有GDM病史的女性进行产后糖尿病定期筛查,但美国妇产科医师学会(ACOG)的指导性没那么强。我们试图研究被诊断为GDM的女性的产后血糖检测情况。

方法

我们对2000年至2001年期间在两个大型学术医疗中心之一被诊断为GDM的女性进行了一项观察性队列研究。确定了从分娩到首次产后DM筛查测试的时间的Kaplan-Meier估计值,并使用Cox比例风险测试检查了产后DM筛查的预测因素。

结果

只有37%的符合条件的女性接受了美国糖尿病协会推荐的产后糖尿病筛查测试(空腹血糖或口服葡萄糖耐量试验[OGTT]),从分娩到首次此类测试的中位时间为428天。相比之下,94%的女性使用巴氏(Pap)试验进行了产后宫颈癌筛查,从分娩到Pap检测的中位时间为49天。即使将随机血糖检测纳入产后DM筛查的广泛定义(随机或空腹血糖、糖化血红蛋白或OGTT),也只有三分之二的女性(67%)接受了产后血糖评估。

结论

在所研究的人群中,根据美国糖尿病协会发布的指南,只有37%有GDM病史的女性接受了产后DM筛查。有必要努力改善这一高危人群的产后DM筛查。

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