Haynes Jonathan C, Farrell Michael, Singleton Nicola, Meltzer Howard, Araya Ricardo, Lewis Glyn, Wiles Nicola J
Academic Unit of Psychiatry, Department of Community Based Medicine, University of Bristol, Cotham House, Cotham Hill, Bristol BS6 6JL,UK.
Br J Psychiatry. 2005 Dec;187:544-51. doi: 10.1192/bjp.187.6.544.
Longitudinal studies have been in conclusive in identifying alcohol as a risk factor for anxiety and depression.
To examine whether excessive alcohol consumption is a risk factor for anxiety and depression in the general population, and whether anxiety and depression are risk factors for excessive alcohol consumption.
Data were analysed from the 18-month follow-up of the Psychiatric Morbidity Among Adults Living in Private Households, 2000 survey.
Hazardous and dependent drinking were not associated with onset of anxiety and depression at follow-up. Binge-drinking was non-significantly associated with incident anxiety and depression (adjusted OR=1.36, 95% CI 0.74-2.50). Abstainers were less likely to have new-onset anxiety and depression at follow-up. Anxiety and depression or sub-threshold symptoms at baseline were not associated with incident hazardous or binge-drinking at follow-up, but there was weak evidence linking sub-threshold symptoms with onset of alcohol dependence (adjusted OR=2.04, 95% CI 0.84-4.97).
Excessive alcohol consumption was not associated with the onset of anxiety and depression but abstinence was associated with a lower risk. Sub-threshold symptoms were weakly associated with new-onset alcohol dependence.
纵向研究在确定酒精是否为焦虑和抑郁的风险因素方面尚无定论。
探讨过量饮酒是否为普通人群焦虑和抑郁的风险因素,以及焦虑和抑郁是否为过量饮酒的风险因素。
对2000年私人住户中成年人精神疾病调查18个月随访的数据进行分析。
危险饮酒和依赖饮酒与随访时焦虑和抑郁的发作无关。暴饮与偶发性焦虑和抑郁无显著关联(调整后比值比=1.36,95%可信区间0.74-2.50)。在随访时,戒酒者新发焦虑和抑郁的可能性较小。基线时的焦虑、抑郁或阈下症状与随访时偶发的危险饮酒或暴饮无关,但有微弱证据表明阈下症状与酒精依赖的发作有关(调整后比值比=2.04,95%可信区间0.84-4.97)。
过量饮酒与焦虑和抑郁的发作无关,但戒酒与较低风险相关。阈下症状与新发酒精依赖有微弱关联。