Heylen E, Simon B, Guerrero F, Elkaïm J-P, Saïag B, Mansourati J
E.A. 3879 Unité de Physiologie Comparée et Intégrative, U.F.R. Sport et Education Physique, 20 avenue Le Gorgeu C.S. 93837, 29238 Brest Cedex 3, France.
Int J Sports Med. 2005 Dec;26(10):822-6. doi: 10.1055/s-2005-837452.
We undertook this study to determine whether long-term high intensity exercise would modify cutaneous endothelial-dependent vasodilation. We compared a group of 9 highly trained windsurfers (mean age: 24.5 +/- 1.6 years) to a control group of 8 sedentary individuals (22.9 +/- 0.4 years, NS). Laser Doppler was used to measure cutaneous blood flow in the resting state (baseline), during post-occlusive hyperaemia (endothelium-dependent vasodilation), and local heating to 42 degrees C. Lipid profile was similar in both groups. Resting heart rate was significantly lower in windsurfers. Baseline cutaneous vascular conductance (CVC) values were similar in both groups (0.059 +/- 0.016 and 0.051 +/- 0.009). During reactive hyperaemia, normalized peak CVC value was significantly higher in the windsurfers group (1775.4 +/- 286.9 and 826.4 +/- 121.7 % baseline CVC; p = 0.01). Normalized peak CVC value in response to local heating (42 degrees C) was not significantly different between both groups (2359.4 +/- 346.1 and 1467.7 +/- 282.6 % baseline CVC). Endothelium-dependent vasodilation in cutaneous microcirculation is significantly enhanced in the forearm skin of highly trained windsurfers when compared to sedentary controls.
我们开展这项研究以确定长期高强度运动是否会改变皮肤内皮依赖性血管舒张功能。我们将一组9名训练有素的风帆冲浪者（平均年龄：24.5±1.6岁）与一组8名久坐不动的个体（22.9±0.4岁，无显著差异）进行比较。使用激光多普勒测量静息状态（基线）、闭塞后充血（内皮依赖性血管舒张）期间以及局部加热至42℃时的皮肤血流量。两组的血脂谱相似。风帆冲浪者的静息心率显著较低。两组的基线皮肤血管传导率（CVC）值相似（0.059±0.016和0.051±0.009）。在反应性充血期间，风帆冲浪者组的标准化峰值CVC值显著更高（分别为基线CVC的1775.4±286.9%和826.4±121.7%；p = 0.01）。两组对局部加热（42℃）的反应中，标准化峰值CVC值无显著差异（分别为基线CVC的2359.4±346.1%和1467.7±282.6%）。与久坐对照组相比，训练有素的风帆冲浪者前臂皮肤的皮肤微循环中内皮依赖性血管舒张功能显著增强。
