Karsten Agneta, Larson Margareta, Larson Ola
Department of Orthodontics, Section for Jaw Orthopedics, Karolinska Institutet, Huddinge, Sweden.
Scand J Plast Reconstr Surg Hand Surg. 2005;39(5):283-6. doi: 10.1080/02844310500223945.
We studied severity of the isolated cleft palate expressed as the length of the cleft in relation to hypodontia in the second premolar regions and known inheritance of any type of cleft lip and palate. The material consisted of 47 children at 10 years of age born with non-syndromic isolated cleft palate of varying extent, who all had hypodontia of at least one second premolar, and had panoramic radiographs taken at 10 years of age. Information about length of cleft and inheritance of cleft lip and palate was collected from surgical files initiated at birth. The higher the number of missing second premolars, the more extended was the length of the cleft. More children had hypodontia of the second premolar in the mandible than in the maxilla. The family history had little influence on the length of the cleft.
我们研究了单纯腭裂的严重程度，以腭裂长度与第二前磨牙区牙缺失情况的关系以及任何类型唇腭裂的已知遗传情况来表示。研究材料包括47名10岁儿童，他们出生时患有不同程度的非综合征性单纯腭裂，均至少有一颗第二前磨牙缺失，并在10岁时拍摄了全景X线片。腭裂长度和唇腭裂遗传信息从出生时开始的手术档案中收集。第二前磨牙缺失数量越多，腭裂长度越长。下颌第二前磨牙缺失的儿童比上颌的更多。家族史对腭裂长度影响不大。
