Tsuchiya Luine R R V, Costa Libera M D, Raboni Sonia M, Nogueira Meri B, Pereira Luciane A, Rotta Indianara, Takahashi Gislene R A, Coelho Micheli, Siqueira Marilda M
Laboratory of Virology, Hospital de Clínicas da Universidade Federal do Paraná, Brazil.
J Infect. 2005 Dec;51(5):401-7. doi: 10.1016/j.jinf.2004.12.002. Epub 2005 Jan 21.
Viral infection is the major cause of respiratory tract pathology affecting individuals of all ages, especially children and immunocompromised patients. There is a paucity of data on etiological and epidemiological infection caused by virus, in Southern Brazil. The aim of this study was to evaluate the seasonality, and the incidence of the viruses involved in respiratory infections in Curitiba, South Brazil.
Two hundred seventy-three nasopharyngeal aspirates (NPA) from primary care health units and 1348 NPA or bronchoalveolar lavages from a tertiary-care teaching hospital were studied. Viruses were identified by indirect immunofluorescence and cellular culture.
Thirty percent of tested samples scored positive for the presence of virions. The percentages of infection for each virus from outpatients and hospitalized, respectively, were 3.3, 19.3 for respiratory syncytial virus; 13.9, 3.5 for influenza A, 3.0, 1.7 for influenza B; 3.3, 5.6 for parainfluenza virus and 2.2, 0.8 for adenovirus. A higher incidence of positive results was found during the winter season, thus showing a pattern of seasonality.
Viral agents are one of the main etiologies of respiratory tract pathology in the population studied.
病毒感染是影响各年龄段人群，尤其是儿童和免疫功能低下患者呼吸道病变的主要原因。巴西南部关于病毒引起的感染病因和流行病学的数据匮乏。本研究的目的是评估巴西南部库里蒂巴呼吸道感染相关病毒的季节性和发病率。
对来自基层医疗保健单位的273份鼻咽抽吸物（NPA）以及一家三级护理教学医院的1348份NPA或支气管肺泡灌洗样本进行了研究。通过间接免疫荧光和细胞培养鉴定病毒。
30%的检测样本病毒粒子呈阳性。门诊患者和住院患者中每种病毒的感染率分别为：呼吸道合胞病毒3.3%、19.3%；甲型流感13.9%、3.5%；乙型流感3.0%、1.7%；副流感病毒3.3%、5.6%；腺病毒2.2%、0.8%。冬季阳性结果的发生率更高，呈现出季节性模式。
在所研究人群中，病毒是呼吸道病变的主要病因之一。
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