Martín Pérez E, Serrano Sánchez P A, Larrañaga Barrera E
Servicio de Cirugía General y Aparato Digestivo, Hospital de la Princesa, Madrid.
Rev Esp Enferm Dig. 1992 Jun;81(6):393-7.
We present a retrospective study on 610 patients with colorectal cancer diagnosed over a 10 year period; 21 patients (3.4%) had synchronous multiple primary carcinomas. Age and clinical symptoms were similar to those with single carcinomas. In 57% of patients, the presence of synchronous neoplasms was diagnosed preoperatively by colonoscopy and/or barium enema, in 38% peroperatively and in 5% postoperatively. The more frequent localizations were rectum-sigmoid colon (24%) and descendent colon-sigmoid colon (19%). Three patients had 3 synchronous tumors, respectively. According to the Dukes classification, 80% of the patients had stage B or C. The five-year survival rate was 61%, similar to that for colon cancer in general. We emphasize the importance of preoperative identification of synchronous lesions; the whole colon should be investigated before surgery in order to ensure that no synchronous tumor has been missed or to change planned surgery.
我们对610例在10年期间被诊断为结直肠癌的患者进行了一项回顾性研究;21例患者(3.4%)患有同时性多原发性癌。年龄和临床症状与单发癌患者相似。57%的患者术前通过结肠镜检查和/或钡剂灌肠诊断出同时性肿瘤,38%在手术中诊断出,5%在术后诊断出。较常见的部位是直肠-乙状结肠(24%)和降结肠-乙状结肠(19%)。三名患者分别有3个同时性肿瘤。根据Dukes分类,80%的患者为B期或C期。五年生存率为61%,与一般结肠癌相似。我们强调术前识别同时性病变的重要性;手术前应检查整个结肠,以确保没有遗漏同时性肿瘤或改变计划的手术方式。