Taguchi Akira, Tsuda Mikio, Ohtsuka Masahiko, Kodama Ichiro, Sanada Mitsuhiro, Nakamoto Takashi, Inagaki Koji, Noguchi Toshihide, Kudo Yoshiki, Suei Yoshikazu, Tanimoto Keiji, Bollen Anne-Marie
Department of Oral and Maxillofacial Radiology, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, 734-8553 Hiroshima, Japan.
Osteoporos Int. 2006;17(3):387-94. doi: 10.1007/s00198-005-2029-7. Epub 2005 Dec 6.
Eroded or thin inferior cortex of the mandible detected on dental panoramic radiographs may be useful for identifying postmenopausal women with low bone mineral density (BMD) or osteoporosis. The purpose of this study was to evaluate whether these panoramic measurements are useful for identifying low BMD or osteoporosis in postmenopausal women younger than 65 years.
We compared the diagnostic performances of panoramic measurements with those of the osteoporosis self-assessment tool (OST) for identifying women with low BMD (T-score of -2.0 or less at either the lumbar spine or the femoral neck) and osteoporosis (T score of -2.5 or less) in 158 healthy Japanese postmenopausal women aged 46 years to 64 years. Mandibular cortical shape (erosion) and width were evaluated on dental panoramic radiographs. Receiver operating characteristic curve analysis was used to determine the optimal cutoff thresholds for cortical width and OST index.
The sensitivity and specificity, respectively, for identifying women with low BMD were 82.3% and 55.2% for OST index, 79.0% and 50.0% for cortical width, and 72.6% and 74.0% for cortical shape. The sensitivity and specificity, respectively, for identifying women with osteoporosis were 86.7% and 46.9% for OST index, 90.0% and 45.3% for cortical width, and 86.7% and 65.6% for cortical shape. Likelihood ratio for identifying women with low BMD was 13.90 for thin cortical width (<3.0 mm) and 10.84 for severely eroded cortex. That for identifying women with osteoporosis was 6.40 for thin cortical width and 7.11 for severely eroded cortex.
Dentists may be able to refer postmenopausal women younger than 65 years for bone densitometry on the basis of incidental findings on dental panoramic radiographs.
牙科全景X线片上检测到的下颌骨皮质侵蚀或变薄可能有助于识别骨矿物质密度(BMD)低或患有骨质疏松症的绝经后女性。本研究的目的是评估这些全景测量对于识别65岁以下绝经后女性的低BMD或骨质疏松症是否有用。
我们比较了全景测量与骨质疏松症自我评估工具(OST)在识别158名年龄在46岁至64岁之间的健康日本绝经后女性低BMD(腰椎或股骨颈T值为-2.0或更低)和骨质疏松症(T值为-2.5或更低)方面的诊断性能。在牙科全景X线片上评估下颌骨皮质形状(侵蚀)和宽度。采用受试者操作特征曲线分析来确定皮质宽度和OST指数的最佳截断阈值。
对于识别低BMD女性,OST指数的敏感性和特异性分别为82.3%和55.2%,皮质宽度分别为79.0%和50.0%,皮质形状分别为72.6%和74.0%。对于识别骨质疏松症女性,OST指数的敏感性和特异性分别为86.7%和46.9%,皮质宽度分别为90.0%和45.3%,皮质形状分别为86.7%和65.6%。识别低BMD女性的似然比,皮质宽度薄(<3.0 mm)为13.90,皮质严重侵蚀为10.84。识别骨质疏松症女性的似然比,皮质宽度薄为6.40,皮质严重侵蚀为7.11。
牙医或许能够根据牙科全景X线片上的偶然发现,将65岁以下的绝经后女性转诊进行骨密度测定。