Seki Keisuke, Nagasaki Maki, Yoshino Tona, Yano Mayuko, Kawamoto Aki, Shimizu Osamu
Department of Comprehensive Dentistry and Clinical Education, Nihon University School of Dentistry, 1-8-13, Kanda-Surugadai, Chiyoda-ku, Tokyo 101-8310, Japan.
Division of Dental Education, Dental Research Center, Nihon University School of Dentistry, 1-8-13, Kanda-Surugadai, Chiyoda-ku, Tokyo 101-8310, Japan.
Diagnostics (Basel). 2024 May 13;14(10):1009. doi: 10.3390/diagnostics14101009.
Osteoporosis is often detected late and becomes severe because of a lack of subjective symptoms. Digital panoramic radiography (DPR) has been reported to be useful for osteoporosis screening based on the morphological classification of the mandibular inferior cortex. The purpose of this study was to evaluate the sensitivity and specificity of the mandibular cortical index (MCI) in the diagnosis of osteoporosis in a group of patients who were and were not using antiosteoporosis medication (AOM). Three hundred and fifty female patients aged 40 years or older who had DPR imaging performed during a 6-year period from December 2015 to February 2022 met the selection criteria. Two examiners recorded mandibular cortical width and MCI from the images. These results were statistically examined together with the patients' demographic data. Forty-nine patients were using AOM (13 nonbisphosphonate/denosumab and 36 bisphosphonate/denosumab). MCI type 3 was the most common in the AOM group. In the MCI classification, DPR imaging among the AOM group was more sensitive (0.95) than that of the control group. This method of estimating osteoporosis based on MCI classification using DPR images has high sensitivity, especially in patients using AOM, suggesting that this method is useful as a screening test.
骨质疏松症往往因缺乏主观症状而被发现较晚且病情严重。据报道，数字全景X线摄影（DPR）基于下颌骨下缘皮质的形态学分类，对骨质疏松症筛查有用。本研究的目的是评估下颌骨皮质指数（MCI）在一组正在使用和未使用抗骨质疏松药物（AOM）的患者中诊断骨质疏松症的敏感性和特异性。在2015年12月至2022年2月的6年期间接受DPR成像的350名40岁及以上女性患者符合入选标准。两名检查人员从图像中记录下颌骨皮质宽度和MCI。这些结果与患者的人口统计学数据一起进行统计学检验。49名患者正在使用AOM（13名使用非双膦酸盐/地诺单抗，36名使用双膦酸盐/地诺单抗）。MCI 3型在AOM组中最为常见。在MCI分类中，AOM组中DPR成像的敏感性（0.95）高于对照组。这种基于DPR图像的MCI分类评估骨质疏松症的方法具有较高的敏感性，尤其是在使用AOM的患者中，表明该方法作为一种筛查测试是有用的。
