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锥形束计算机断层扫描全景下颌骨指数在绝经后低骨量女性筛查中的应用:与骨量和骨质量的相关性

Cone Beam Computed Tomography Panoramic Mandibular Indices in the Screening of Postmenopausal Women with Low Bone Mass: Correlations with Bone Quantity and Quality.

作者信息

Poiană Ioana Ruxandra, Burcea Iulia Florentina, Pițuru Silviu-Mirel, Bucur Alexandru

机构信息

Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.

出版信息

Dent J (Basel). 2024 Aug 14;12(8):256. doi: 10.3390/dj12080256.

Abstract

OBJECTIVE

This study examined the potential use of computed tomography panoramic mandibular indices on cone beam CT (CBCT) for assessing bone density in postmenopausal women with low bone mass.

STUDY DESIGN

The study enrolled 104 postmenopausal women who underwent dual-energy X-ray absorptiometry (DXA) using a DXA scanner and mental foramen region CBCT alongside the NewTom VGi EVO Cone Beam 3D system. We assessed the relationship between the following DXA parameters: lumbar, femoral neck, and total hip T score, bone mineral density (BMD), and lumbar trabecular bone score (TBS). The following panoramic mandibular indices were also considered: the computed tomography mandibular index superior (CTI(S)), computed tomography mandibular index inferior (CTI(I)), and computed tomography mental index (CTMI).

RESULTS

The study revealed moderate correlations between CBCT indices and BMD/TBS scores: CTMI showed the highest correlation with the femoral neck T-score (r = 0.551, < 0.0001). TBS scores were also moderately correlated with CBCT indices: CTMI showed a moderate positive correlation with TBS (r = 0.431, < 0.0001); CTI(S) had a similar moderate positive correlation with TBS (r = 0.421, < 0.0001). AUC values ranged from 0.697 to 0.733 for osteoporosis versus the osteopenia/normal group and from 0.734 to 0.744 for low versus normal bone quality groups, < 0.0001. The comparison of the values of the studied indices between low versus normal bone quality (quantified with TBS) groups showed high sensitivity but low specificity.

CONCLUSIONS

CBCT-measured indices CTI(S), CTI(I), and CTMI are useful in assessing patients with low bone mass to improve, by specific treatment, the prognosis of dental implants.

摘要

目的

本研究探讨锥形束计算机断层扫描(CBCT)上的计算机断层扫描全景下颌骨指数在评估低骨量绝经后女性骨密度方面的潜在用途。

研究设计

该研究纳入了104名绝经后女性,她们使用双能X线吸收法(DXA)扫描仪进行了双能X线吸收测定,并使用NewTom VGi EVO锥形束三维系统对颏孔区域进行了CBCT扫描。我们评估了以下DXA参数之间的关系:腰椎、股骨颈和全髋部T值、骨矿物质密度(BMD)以及腰椎小梁骨评分(TBS)。还考虑了以下全景下颌骨指数:计算机断层扫描下颌骨上指数(CTI(S))、计算机断层扫描下颌骨下指数(CTI(I))和计算机断层扫描颏指数(CTMI)。

结果

研究揭示了CBCT指数与BMD/TBS评分之间存在中度相关性:CTMI与股骨颈T值的相关性最高(r = 0.551,< 0.0001)。TBS评分也与CBCT指数存在中度相关性:CTMI与TBS呈中度正相关(r = 0.431,< 0.0001);CTI(S)与TBS也有类似的中度正相关(r = 0.421,< 0.0001)。骨质疏松症与骨质减少/正常组的AUC值范围为0.697至0.733,低骨质量与正常骨质量组的AUC值范围为0.734至0.744,< 0.0001。低骨质量(用TBS量化)组与正常骨质量组之间研究指数值的比较显示出高敏感性但低特异性。

结论

CBCT测量的指数CTI(S)、CTI(I)和CTMI有助于评估低骨量患者,通过特定治疗改善牙种植体的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a991/11353085/9202f60e22a0/dentistry-12-00256-g001.jpg

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