Jones Ticora V, Slutsky Morris M, Laos Roberto, de Greef Tom F A, Tew Gregory N
Polymer Science & Engineering, University of Massachusetts, Amherst, Massachusetts 01003, USA.
J Am Chem Soc. 2005 Dec 14;127(49):17235-40. doi: 10.1021/ja053530+.
Oligomers based on an o-phenylene ethynylene (oPE) backbone with polar substituents have been synthesized using Sonogashira methods. Folding of these extremely short oligomers was confirmed via 1D and 2D (NOESY) NMR methods. Utilizing electron-rich and electron-poor phenylene building blocks, variations of these oPE oligomers have been synthesized to determine the folded stability of pi-rich vs pi-poor vs pi-rich-pi-poor systems. Slight variations in temperature offer a route, aside from solvent denaturation, to probe the stability of the folded structure. This is the first report of an NMR solution characterization of folding for a PE backbone without hydrogen bonds.
基于带有极性取代基的邻亚苯基乙炔（oPE）主链的低聚物已通过Sonogashira方法合成。这些极短低聚物的折叠通过一维和二维（NOESY）核磁共振方法得到证实。利用富电子和贫电子的亚苯基结构单元，合成了这些oPE低聚物的变体，以确定富π与贫π与富π - 贫π体系的折叠稳定性。除了溶剂变性之外，温度的微小变化提供了一种探究折叠结构稳定性的途径。这是关于无氢键的PE主链折叠的核磁共振溶液表征的首次报道。
