Nieto García A, Guix García J, Navarro Ibáñez V, Roig Rico P, Bernacer Alpera B
Unidad de Enfermedades Infecciosas, Hospital General Universitario, Valencia.
An Med Interna. 1992 Jul;9(7):318-21.
We present a prospective follow-up study of 114 patient infected by Candida and HIV, in order to assess the role of oral candidiasis (OC) as a predictive marker of tuberculosis and opportunistic infections (OI) which define the Acquired Immunodeficiency Syndrome (AIDS). We compared the study group with an homogeneous control group of 152 patients infected by HIV without OC during the same period. TBC findings in the first group were discriminant with respect to the control group (p less than 0.0001) with and average period of 2.5 months between the diagnosis of OC and the development of TBC. These findings suggest that OC is an early evolutive marker of TBC and a late marker of AIDS.
