Schulten E A, ten Kate R W, van der Waal I
Department of Oral and Maxillofacial Surgery, Free University Hospital/Academic Centre, Amsterdam, The Netherlands.
Q J Med. 1990 Jul;76(279):741-5.
The occurrence of oral mucosal lesions was studied in 70 consecutive human immunodeficiency virus (HIV)-infected patients, including 35 patients with AIDS, who had been admitted to a Department of Internal Medicine. Lesions of the oral mucosa were observed in 52 patients (74 per cent). Oral candidiasis (50 per cent), hairy leukoplakia (14 per cent), periodontal disease (13 per cent), and oral Kaposi's sarcoma (4 per cent) were the most common lesions. Oral mucosal lesions suggestive of HIV infection were present in ten of 12 patients of unknown HIV status in whom Pneumocystis carinii pneumonia was suspected. Close cooperation between the medical and dental professions is recommended since accurate intraoral examination can make a valuable contribution towards the clinical management of HIV-infected patients and may influence the CDC classification of this disease.
对70例连续入住内科的人类免疫缺陷病毒（HIV）感染患者进行了口腔黏膜病变研究，其中包括35例艾滋病患者。52例患者（74%）观察到口腔黏膜病变。口腔念珠菌病（50%）、毛状白斑（14%）、牙周病（13%）和口腔卡波西肉瘤（4%）是最常见的病变。在12例疑似卡氏肺孢子虫肺炎但HIV感染状况不明的患者中，有10例存在提示HIV感染的口腔黏膜病变。建议医学和牙科专业密切合作，因为准确的口腔检查可为HIV感染患者的临床管理做出重要贡献，并可能影响疾病控制与预防中心（CDC）对该疾病的分类。
