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血管平滑肌功能的调控:我与E.E. 丹尼尔教授的终身学习与不断探索

The control of vascular smooth muscle function: my life-long learning and continuous discovery with Professor E.E. Daniel.

作者信息

Kwan Chiu-Yin

机构信息

Department of Medicine and Smooth Muscle Research Program, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.

出版信息

Can J Physiol Pharmacol. 2005 Aug-Sep;83(8-9):669-74. doi: 10.1139/y05-074.

DOI:10.1139/y05-074
PMID:16333369
Abstract

This communication is neither a comprehensive review of my research, nor a description about my recent new original scientific findings in smooth muscle or in cell Ca2+. For that intention, I will choose to publish via a regular channel, certainly not in this special edition. My intention is to take this opportunity to recapitulate Dr. Daniel's thoughts and spirits through the progress of my research, teaching, and personal development at McMaster University, stemming largely from Dr. Daniel's life-long interest in the regulation of Ca2+ in the control of smooth muscle function, specifically the vascular smooth muscle. Being a culturally adsorbent person, I am sure that my thoughts and behavior must have been substantially influenced by Dr. Daniel over 27 years of our collaboration. His influence may have molded me into whom and what I am today, both socially and scientifically. Equally, I may also have influenced him in some particular or peculiar way. Dr. Daniel's academic contribution is globally well known for, but not limited to, his insightful and productive research in smooth muscle, but also for his effective application of problem-based learning to education in pharmacology and his influence on students and colleagues.

摘要

这篇交流文章既不是对我研究的全面综述,也不是对我近期在平滑肌或细胞钙方面新的原创科学发现的描述。出于这个目的,我会选择通过常规渠道发表,肯定不会在这个特刊上。我的目的是借这个机会,通过我在麦克马斯特大学的研究、教学和个人发展历程,来概括丹尼尔博士的思想和精神,这很大程度上源于丹尼尔博士对平滑肌功能控制中钙调节的毕生兴趣,特别是血管平滑肌。作为一个有文化吸收能力的人,我确信在我们27年的合作中,我的思想和行为一定受到了丹尼尔博士的极大影响。他的影响可能在社会和科学层面上塑造了今天的我。同样,我可能也以某种特殊或独特的方式影响了他。丹尼尔博士的学术贡献在全球都广为人知,这不仅体现在他在平滑肌方面富有洞察力和成果丰硕的研究,还体现在他将基于问题的学习有效地应用于药理学教育以及他对学生和同事的影响。

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