Celis Zapata Juan, Berrospi Espinoza Francisco, Ruiz Figueroa Eloy, Payet Meza Eduardo, Chavez Passiuri Iván, Young Tabusso Frank
Departamento de Abdomen, Instituto Especializado de Enfermedades Neoplásicas.
Rev Gastroenterol Peru. 2005 Oct-Dec;25(4):349-55.
Proximal or distal pancreatectomy is the standard treatment for non-resectable benign pancreatic tumors. These procedures imply a radical resection as well as a significant loss of distal normal pancreatic tissue for the standard resection, which may cause an endocrine and/or exocrine pancreatic failure.
Report our experience in central pancreatectomy for the treatment of benign/low malignancy potential tumors in the body and neck of the pancreas by emphasizing the indications and perisurgical results.
Prospective study of patients with suspected benign tumors in the body of pancreas.
Resection of central pancreas through a Roux-en-Y pancreatojejunal anastomosis.
From March 1997 to May 2005, 12 patients underwent central pancreatectomy through pancreatojejunal anastomosis. 6 benign tumors were found in the islets of Langerhans: 3 microcystic cystadenomas, 1 mucinous cystadenoma, 1 pseudopapillary solid tumor, and 1 serous cystadenoma. Morbidity rate was 33.3% with no post-surgery deaths. Pancreatic failure was not reported during follow up.
Some selected cases of benign/low malignancy potential tumors may be treated with central pancreatectomy and pancreatojejunal anastomosis with acceptable morbidity levels and minimum mortality levels. The benefit from preserving the greatest extension of healthy pancreatic tissue as possible is translated into a preservation of the endocrine and exocrine functions of the pancreas.
近端或远端胰腺切除术是不可切除的良性胰腺肿瘤的标准治疗方法。这些手术意味着根治性切除,同时标准切除会导致远端正常胰腺组织大量丢失,这可能会引起胰腺内分泌和/或外分泌功能衰竭。
报告我们采用中央胰腺切除术治疗胰腺体部和颈部良性/低恶性潜能肿瘤的经验,重点阐述手术指征和围手术期结果。
对疑似胰腺体部良性肿瘤患者进行前瞻性研究。
通过 Roux-en-Y 胰空肠吻合术切除胰腺中部。
1997 年 3 月至 2005 年 5 月,12 例患者通过胰空肠吻合术接受了中央胰腺切除术。在胰岛中发现 6 个良性肿瘤:3 个微囊性囊腺瘤、1 个黏液性囊腺瘤、1 个实性假乳头状肿瘤和 1 个浆液性囊腺瘤。发病率为 33.3%,无术后死亡病例。随访期间未报告胰腺功能衰竭。
一些选定的良性/低恶性潜能肿瘤病例可以采用中央胰腺切除术和胰空肠吻合术进行治疗,发病率可接受,死亡率最低。尽可能保留最大范围健康胰腺组织的益处体现为胰腺内分泌和外分泌功能的保留。